L-Tryptophan methyl esterCAS# 4299-70-1 |
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Number of papers citing our products

| Cas No. | 4299-70-1 | SDF | File under preparation. |
| PubChem ID | N/A | Appearance | Powder |
| Formula | C12H14N2O2 | M.Wt | 218.3 |
| Type of Compound | Alkaloids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
L-Tryptophan methyl ester Dilution Calculator
L-Tryptophan methyl ester Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 4.5809 mL | 22.9043 mL | 45.8085 mL | 91.617 mL | 114.5213 mL |
| 5 mM | 0.9162 mL | 4.5809 mL | 9.1617 mL | 18.3234 mL | 22.9043 mL |
| 10 mM | 0.4581 mL | 2.2904 mL | 4.5809 mL | 9.1617 mL | 11.4521 mL |
| 50 mM | 0.0916 mL | 0.4581 mL | 0.9162 mL | 1.8323 mL | 2.2904 mL |
| 100 mM | 0.0458 mL | 0.229 mL | 0.4581 mL | 0.9162 mL | 1.1452 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Surface Plasmon Resonance Sensors Based on the Molecularly Imprinted Technique for Simvastatin Detection.[Pubmed:41552491]
ACS Omega. 2025 Dec 22;11(1):833-843.
In this study, surface plasmon resonance (SPR)-based sensors were developed to determine simvastatin (SIM) with phosphate buffer (pH 7.4) using the molecular imprinting technique (MIT). SIM imprinted (MIP) and nonimprinted (NIP) poly-(2-hydroxyethyl methacrylate-N-methacryloyl-L-Tryptophan methyl ester) polymeric films were synthesized onto the surface of the SPR chips to obtain kinetic parameters. The characterization of the MIP and NIP sensors was determined by contact angle and atomic force microscopy measurements. The range of linearity was measured as 0.001-1.0 mg/mL for SIM imprinted polymeric film-based SPR sensors. The selectivity of SPR sensors for competitive adsorption of atorvastatin and rosuvastatin was also investigated. After optimizing the experimental studies for SIM determination, SIM determination was also performed in artificial plasma solutions, and the recoveries were calculated to be approximately 99%. The findings indicate that SIM imprinted SPR sensors demonstrate exceptional sensitivity and selectivity along with a remarkably low detection limit for precise target identification.
In Vitro Study of Antiviral Properties of Compounds Based on 1,4-Dioxane Derivative of Closo-Decaborate Anion with Amino Acid Ester Residues Against Influenza Virus A/IIV-Orenburg/83/2012(H1N1)pdm09.[Pubmed:39769975]
Molecules. 2024 Dec 13;29(24):5886.
New derivatives of the closo-decaborate anion [B(10)H(9)-O(CH(2))(2)O(CH(2))(3)C(O)-L-OCH(3)](2-) (An) (1: L = Trp; 2: L = His; 3: L = Met; 4: L = Ala(2-oxopyrrolidin-3-yl) (Pld) were synthesized and isolated as tetraphenylphosphonium salts (Ph(4)P)(2)An. Anions 1(2-); 2(2-); 3(2-), and 4(2-) contain a pendant functional group from the L-Tryptophan methyl ester, L-histidine methyl ester, L-methionine methyl ester, or methyl 2-amino-3-(2-oxopyrrolidin-3-yl)propanoate (-Trp-OCH(3), -His-OCH(3), -Met-OCH(3), or -Pld-OCH(3)) residue, respectively, bonded with the boron cluster anion through the oxybis[(ethane-2,1-diyl)oxy] spacer. This pacer is formed as a result of the nucleophilic opening of the attached dioxane molecule in the [B(10)H(9)O(CH(2))(4)O](-) starting derivative. Sodium salts of the target compounds were isolated and used in biological experiments. It was established that among compounds Na(2)An (An = 1-4), not all are capable of inhibiting the cytopathic effect of the virus in vitro. Sodium salts Na(2)An have a low toxic effect on a monolayer of continuous canine embryonic kidney (MDCK) cell line. Compounds Na(2)1 and Na(2)2 had IC(50) of 5.0 and 20.0 mug/mL, respectively, while for compounds Na(2)3 and Na(2)4, IC(50) values could not be achieved at the concentrations studied. The studies performed for molecular docking of the anionic part of 1(2-) and 2(2-) with the transmembrane domain of viroporin M2 show some differences in the location of these two ligands inside the M2 canal pore.


