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7alpha-Hydroxydehydroabietic acid

CAS# 76235-98-8

7alpha-Hydroxydehydroabietic acid

2D Structure

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7alpha-Hydroxydehydroabietic acid: 5mg $200 In Stock
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7alpha-Hydroxydehydroabietic acid

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Chemical Properties of 7alpha-Hydroxydehydroabietic acid

Cas No. 76235-98-8 SDF File under preparation.
PubChem ID N/A Appearance Powder
Formula C20H28O3 M.Wt 316.4
Type of Compound Diterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of 7alpha-Hydroxydehydroabietic acid

The herbs of Pinus massoniana

7alpha-Hydroxydehydroabietic acid Dilution Calculator

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7alpha-Hydroxydehydroabietic acid Molarity Calculator

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Preparing Stock Solutions of 7alpha-Hydroxydehydroabietic acid

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.1606 mL 15.8028 mL 31.6056 mL 63.2111 mL 79.0139 mL
5 mM 0.6321 mL 3.1606 mL 6.3211 mL 12.6422 mL 15.8028 mL
10 mM 0.3161 mL 1.5803 mL 3.1606 mL 6.3211 mL 7.9014 mL
50 mM 0.0632 mL 0.3161 mL 0.6321 mL 1.2642 mL 1.5803 mL
100 mM 0.0316 mL 0.158 mL 0.3161 mL 0.6321 mL 0.7901 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on 7alpha-Hydroxydehydroabietic acid

[Diterpenoids from Rabdosia flexicaulis].[Pubmed:35178986]

Zhongguo Zhong Yao Za Zhi. 2022 Jan;47(2):433-436.

The genus Rabdosia is famous for the abundance of diverse and novel ent-kaurane diterpenoids. However, only a few ent-kauranoids have been discovered from R. flexicaulis since the investigation on its chemical constituents is not systematic. To find novel bioactive diterpenoids, the ethyl acetate extract of the above ground part of R. flexicaulis in Daofu County, Sichuan Province was obtained by column chromatography. One new compound and five known ones were identified as flexicaulin E(1), forrestin B(2), inf-lexarabdonin D(3), 7alpha-Hydroxydehydroabietic acid(4), 15-hydroxydehydroabietic acid(5), and pomiferin F(6) by spectral techniques. Compounds 1-3 were the ent-kaurane diterpenoids isolated from this species for the first time. Compounds 4-6, aromatic abie-tanoids, were isolated from the genus Rabdosia for the first time.

[Studies on diterpenes in needles of Pinus sylvestris].[Pubmed:17348188]

Zhongguo Zhong Yao Za Zhi. 2006 Dec;31(23):1956-9.

OBJECTIVE: To research the constituents in needles of Pinus sylvestris. METHOD: Repeated column chromatography and preparation HPLC are used for compound isolation, and their structures were elucidated on the basis of spectral data analysis. RESULT: Six compounds, pinifolic acid (1), 15-oxo-8 (17) -labden-18-oic acid (2) , 15-acetoxy-labd-8 ( 17)-en-18-oic acid (3), dehydroabietic acid (4), 7alpha-Hydroxydehydroabietic acid (5), 7beta-hydroxydehydroabietic acid (6) were isolated from the needles of P. sylvestris. CONCLUSION: Compound 3-6 were isolated from the needles of P. sylvestris for the first time, and compound 3 is a new natural product. The petroleum ether and EtOAc extracts showed significant cytotoxic effects to Hela and A549. Compounds 2, 4-6 revealed a positive distinction compared to the control group.

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