Hispidulin 7-O-glucuronideCAS# 31105-76-7 |
| Cas No. | 31105-76-7 | SDF | File under preparation. |
| PubChem ID | 5318059 | Appearance | Powder |
| Formula | C22H20O12 | M.Wt | 476.4 |
| Type of Compound | Flavonoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[5-hydroxy-2-(4-hydroxyphenyl)-6-methoxy-4-oxochromen-7-yl]oxyoxane-2-carboxylic acid | ||
| SMILES | COC1=C(C=C2C(=C1O)C(=O)C=C(O2)C3=CC=C(C=C3)O)OC4C(C(C(C(O4)C(=O)O)O)O)O | ||
| Standard InChIKey | GVEZRDBRYNJUDQ-QSUZLTIMSA-N | ||
| Standard InChI | InChI=1S/C22H20O12/c1-31-19-13(33-22-18(28)16(26)17(27)20(34-22)21(29)30)7-12-14(15(19)25)10(24)6-11(32-12)8-2-4-9(23)5-3-8/h2-7,16-18,20,22-23,25-28H,1H3,(H,29,30)/t16-,17-,18+,20-,22+/m0/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
Quality Control & MSDS
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Hispidulin 7-O-glucuronide Dilution Calculator
Hispidulin 7-O-glucuronide Molarity Calculator
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| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.0991 mL | 10.4954 mL | 20.9908 mL | 41.9815 mL | 52.4769 mL |
| 5 mM | 0.4198 mL | 2.0991 mL | 4.1982 mL | 8.3963 mL | 10.4954 mL |
| 10 mM | 0.2099 mL | 1.0495 mL | 2.0991 mL | 4.1982 mL | 5.2477 mL |
| 50 mM | 0.042 mL | 0.2099 mL | 0.4198 mL | 0.8396 mL | 1.0495 mL |
| 100 mM | 0.021 mL | 0.105 mL | 0.2099 mL | 0.4198 mL | 0.5248 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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High-performance thin-layer chromatography combined with effect-directed assays revealed bioactivity profiles of Salvia aegyptiaca, S. verbenaca, and S. officinalis.[Pubmed:40398103]
J Chromatogr B Analyt Technol Biomed Life Sci. 2025 Jul 1;1261:124653.
The effect-directed profiling of aqueous ethanol extracts of Tunisian Salvia aegyptiaca and Salvia verbenaca aerial parts and Tunisian and Hungarian Salvia officinalis leaves was achieved by high-performance thin-layer chromatography (HPTLC) coupled with radical scavenging (using DPPH* free radical) and enzyme inhibitory (acetylcholinesterase, AChE) bioactivity assays. The mixture of toluene - ethyl acetate - methanol - formic acid, 11:2:6:1 (V/V) was used as a mobile phase for the separation of bioactive zones. The characterization of the compounds present in the active zones was performed by derivatization with aluminum chloride or natural product-polyethylene glycol (NP-PEG) reagent, and HPTLC-heated electrospray ionization-high resolution tandem mass spectrometry (HPTLC-HESI-HRMS/MS). Compounds in the nine antioxidant zones could be characterized by derivatization as phenolic compounds and tentatively identified by MS as caffeic acid derivatives, or flavonoid glycosides or glucuronides. Rosmarinic acid and luteolin 7-O-glucuronide were detected in S. aegyptiaca and S. officinalis extracts, while apigenin 7-O-glucuronide and luteolin 7-O-glucoside were identified in S. aegyptiaca and S. verbenaca. The co-presence of an unknown caffeic acid derivative, Hispidulin 7-O-glucuronide and luteolin 7-O-glucoside was proved within a single zone of S. officinalis extract. Additionally, an unknown rosmarinic acid derivative and an unknown luteolin derivative were detected in S. officinalis and S. verbenaca, respectively. These compounds exhibited weak AChE inhibitory activity, with luteolin 7-O-glucuronide demonstrating the strongest effect.
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