ArteanoflavoneCAS# 68710-17-8 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 68710-17-8 | SDF | Download SDF |
| PubChem ID | 14104188 | Appearance | Powder |
| Formula | C19H18O8 | M.Wt | 374.35 |
| Type of Compound | Flavonoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 5,7-dihydroxy-6-methoxy-2-(3,4,5-trimethoxyphenyl)chromen-4-one | ||
| SMILES | COC1=CC(=CC(=C1OC)OC)C2=CC(=O)C3=C(C(=C(C=C3O2)O)OC)O | ||
| Standard InChIKey | ZHESTCBHMHKZNL-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C19H18O8/c1-23-14-5-9(6-15(24-2)19(14)26-4)12-7-10(20)16-13(27-12)8-11(21)18(25-3)17(16)22/h5-8,21-22H,1-4H3 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | Arteanoflavone is a natural product from Artemisia hispanica. |
| Structure Identification | Biomed Res Int. 2017;2017:7375615.Inhibitory Effect of Chemical Constituents Isolated from Artemisia iwayomogi on Polyol Pathway and Simultaneous Quantification of Major Bioactive Compounds.[Pubmed: 28512639 ]Blocking the polyol pathway plays an important role preventing diabetic complications. Therefore, aldose reductase (AR) and advanced glycation endproducts (AGEs) formation has significant effect on diabetic complications. Artemisia iwayomogi has long been used as treatment of various diseases in Korea. However, no literatures have reported on AR and AGEs formation inhibitory activities of A. iwayomogi. For these reasons, we aimed to assess that A. iwayomogi had potential as anti-diabetic complications agents. Phytochemistry, 1988, 27(10):3155-3159.Flavonoids and other phenolics from Artemisia hispanica.[Reference: WebLink]Extraction of aerial parts of Artemisia hispanica and chromatographic separation yielded chrysosplenetin, chrysosplenol D, 5,7,3′,4′-tetrahydroxy-6,5′-dimethoxyflavone, 5,7,3′-trihydroxy-6,4′,5′-trimethoxyflavone, Arteanoflavone, cirsilineol, penduletin, axillarin, jaceosidin, apigenin, luteolin, p-hydroxyacetophenone, 4-(p-hydroxyphenyl) butan-2-one, methyl caffeate, esculetin, apigenin 7-glucoside, luteolin 7-glucoside and the new flavonoids 5,3′,4′-trihydroxy-6,7,5′-trimethoxyflavone and isoetin 5′-glucoside. |
Arteanoflavone Dilution Calculator
Arteanoflavone Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.6713 mL | 13.3565 mL | 26.713 mL | 53.4259 mL | 66.7824 mL |
| 5 mM | 0.5343 mL | 2.6713 mL | 5.3426 mL | 10.6852 mL | 13.3565 mL |
| 10 mM | 0.2671 mL | 1.3356 mL | 2.6713 mL | 5.3426 mL | 6.6782 mL |
| 50 mM | 0.0534 mL | 0.2671 mL | 0.5343 mL | 1.0685 mL | 1.3356 mL |
| 100 mM | 0.0267 mL | 0.1336 mL | 0.2671 mL | 0.5343 mL | 0.6678 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Inhibitory Effect of Chemical Constituents Isolated from Artemisia iwayomogi on Polyol Pathway and Simultaneous Quantification of Major Bioactive Compounds.[Pubmed:28512639]
Biomed Res Int. 2017;2017:7375615.
Blocking the polyol pathway plays an important role preventing diabetic complications. Therefore, aldose reductase (AR) and advanced glycation endproducts (AGEs) formation has significant effect on diabetic complications. Artemisia iwayomogi has long been used as treatment of various diseases in Korea. However, no literatures have reported on AR and AGEs formation inhibitory activities of A. iwayomogi. For these reasons, we aimed to assess that A. iwayomogi had potential as anti-diabetic complications agents. We led to isolation of two coumarins (1 and 2), nine flavonoids (3-11), five caffeoylquinic acids (12-16), three diterpene glycosides (17-19), and one phenolic compound (20) from A. iwayomogi. Among them, hispidulin (4), 6-methoxytricin (6), Arteanoflavone (7), quercetin-3-gentiobioside (10), 1,3-di-O-caffeoylquinic acid (13), and suavioside A (18) were first reported on the isolation from A. iwayomogi. Not only two coumarins (1 and 2), nine flavonoids (3-11), and five caffeoylquinic acids (12-16) but also extracts showed significant inhibitor on AR and AGEs formation activities. We analyzed contents of major bioactive compounds in Korea's various regions of A. iwayomogi. Overall, we selected Yangyang, Gangwon-do, from June, which contained the highest amounts of bioactive compounds, as suitable areas for cultivating A. iwayomogi as preventive or therapeutic agent in the treatment of diabetic complications.
