Products with Inhibitors bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN3961 | 8-Lavandulylkaempferol |
| 1. 8-Lavandulylkaempferol exhibits significant inhibitory effects with IC(50) values of 7.10 and 8.11 microM for butyrylcholinesterase and acetylcholinesterase, respectively. 2. 8-Lavandulylkaempferol shows inhibitory activities against aldose reductase, with the the IC50 of 0.79 microM. | |
| BCN3972 | Guajadial B |
| 1. Guajadial B shows cytotoxicities against five human cancer cell lines, it is the most effective having an IC50 value of 150 nM toward A549 cells. 2. Guajadial B acts as a Top1 catalytic inhibitor and delays Top1 poison-mediated DNA damage. | |
| BCN3985 | Magnolianin |
| 1. Magnolianin can inhibit strongly (IC50 = 0.45 uM) 5-HETE formation by die cytosol of guinea pig polymorphonuclear leukocytes. | |
| BCN4004 | Moracin O |
| 1. Moracin O and moracin P exhibit potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1), which is a key mediator during adaptation of cancer cells to tumour hypoxia. 2. Moracin O shows significant neuroprotective activity against glutamate-induced cell death in SK-N-SH cells. 3. Moracin O demonstrates a remarkable inhibition of the acetic acid-induced pain. 4. Moracin O has a strong protective influence against doxorubicin-induced cardiomyopathy in H9c2 cells with the EC50 value of 4.5 ± 1.3 uM. | |
| BCN4012 | Cyclo(L-Ala-L-Pro) |
| Cyclo(L-Ala-L-Pro) and cyclo(L-Val-L-Pro) inhibit aflatoxin production of Aspergillus parasiticus and Aspergillus flavus in liquid medium at concentrations of several hundred uM without affecting fungal growth. | |
