Products with Inhibitors bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN4278 | Laurifoline |
| 1. Laurifoline is a potential NF-κB inhibitor and a potential β2 -adrenegic receptor agonist, it can not only inhibit Pseudomonas aeruginosa PAK strain-induced inflammatory responses via a negative regulation of the Braf protein that participates in MAPK signaling pathway but also activate the β2 -adrenegic receptor. 2. Laurifoline may show anti-HBV activities in vitro using the HBV transfected Hep G2.2.15 cell line. | |
| BCN4288 | 27-p-Coumaroyloxyursolic acid |
| 1. 27-trans-p-Coumaroyloxyursolic acid and 27-cis-p-coumaroyloxyursolic acid show potent inhibitory activity in the acyl CoA cholesteryl acyl transferase (ACAT) assay. | |
| BCN4290 | Acetylursolic acid |
| Acetylursolic acid shows significant cytotoxic activities, and shows suppression of the SOS-inducing activity of mutagenic heterocyclic amine, Trp-P-1. 3β-Acetylursolic acid can reduce parasitaemia against Plasmodium berghei. | |
| BCN4296 | 8-Geranyloxypsoralen |
| 8-Geranyloxypsoralen inhibits β-secretase (BACE1) activity in non-competitive manner, with the IC(50) values <25.0 uM, it can induce vasorelaxation on rat arterial tissues. 8-Geranyloxypsoralen possesses nematicidal activities, the median lethal concentrations (LC(50)) is 188.3 mg/ L against B. xylophilus and is 117.5 mg/L against P. redivivus. | |
| BCN4306 | (-)-Usnic acid |
| Usnic acid has antitumoral, acaricidal, larvicidal, antiviral, antibiotic, antipyretic, analgesic,gastroprotective, antioxidative and anti-inflammatory activities. Use of reconstituted bovine type-I collagen-based films containing usnic acid can improve burn healing process in rats. Usnic acid perturbs various interrelated signaling pathways and that autophagy induction is a defensive mechanism against usnic acid-induced cytotoxicity; it disturbs calcium homeostasis, induces ER stress, and that Usnic acid-induced cellular damage occurs at least partially via activation of the Ca(2+) channel of SOCE. | |
