Products with Inhibitors bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN4105 | Confluentic acid |
| 1. Confluentic acid shows selective inhibition of Monoamine oxidase B with IC50 value of 0.22 microM. | |
| BCN4111 | Corypalmine |
| 1. Corypalmine (IC50=128.0±10.5 uM) can inhibit prolyl oligopeptidase. 2. (-)-Corypalmine shows inhibition activity against spore germination of some fungi. | |
| BCN4118 | Braylin |
| 1. Braylin has anti-inflammatory, antinociceptive and immunomodulatory effects, which possibly act through the glucocorticoid receptor activation and by inhibition of the transcriptional activity of NF-κB. 2. Braylin is a phosphodiesterase-4 inhibitor, it could represent an ideal prototype of glucocorticoid receptor ligand, able to induce synergic immunomodulatory effects. | |
| BCN4126 | Phlorizin |
| Phlorizin is a non-selective SGLT inhibitor with Kis of 300 and 39 nM for hSGLT1 and hSGLT2, respectively. Phlorizin is also a Na+/K+-ATPase inhibitor. Phlorizin may be a novel therapeutic approach for the treatment of diabetic nephrolog, it protects mice from diabetic nephrology. Phlorizin prevents ventricular tachyarrhythmia through the improvement of impulse conduction slowing during ischemia. | |
| BCN4127 | Guaiacin |
| (+)-Guaiacin has significant neuroprotective, and anti-inflammatory activities, it can inhibit cyclooxygenase (COX)-1 and COX-2. (+)-Guaiacin shows potent in vitro activities against the release of beta-glucuronidase in rat polymorphonuclear leukocytes (PMNs) induced by platelet-activating factor (PAF), with 42.5-75.6% inhibition at 10(-5) M. | |
