Products with Inhibitors bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN5037 | 4-Methoxycinnamic acid |
| 4-Methoxycinnamic acid is a photosensitive compound, it shows various pharmacologic actions such as anti-cancer, hepatoprotective and antihyperglycemic activities, it also can stimulate insulin secretion from pancreatic β-cells by increasing Ca2+ influx via the L-type Ca2+ channels, but not through the closure of ATP-sensitive K+ channels. 4-Methoxycinnamic acid can strongly inhibit the diphenolase activity of mushroom tyrosinase, with the IC 50 value of 0.42 mM, and the inhibition is reversible. | |
| BCN5038 | 2-Methoxycinnamic acid |
| 2-Methoxycinnamic acid is a photosensitive compound. 2-Methoxycinnamic acid can enhance inhibition of tyrosinase activity. | |
| BCN5043 | Methyl cinnamate |
| Methyl cinnamate, a tyrosinase inhibitor and a flavoring compound, which has antimicrobial, antiadipogenic, vasorelaxant, and anti-inflammatory effects. It has a wide spectrum of targets including CaMKK2-AMPK, Ca(2+) channels. | |
| BCN5049 | Cytochalasin D |
| 1. Cytochalasin D-induced extension of neurite-like processes might correlate with enhanced accumulation of PrPres. 2. Cytochalasin D is an actin inhibitor, the removal of actin stress fibers is crucial for the chondrogenic differentiation. 3. Cytochalasin D inhibits CT26 tumor growth potentially through inhibition of cell proliferation, induction of cell apoptosis and suppression of tumor angiogenesis. 4. Cytochalasin D stimulates the expression of TF in B16 melanoma cells, activating both coagulation-dependent and -independent pathways via binding to FVIIa, eventually promoting lung metastasis. 5. Cytochalasin D inhibits smooth muscle contraction by directly inhibiting contractile apparatus. 6. Cytochalasin D is an inhibitor of microfilament-dependent phagocytosis, it (0.5 or 1.0 micrograms/ml) can inhibit intracellular multiplication of L. pneumophila in U937 monocytes. 7. Cytochalasin D may be an inhibitor of some fertilization processes such as sperm penetration or sperm head decondensation. | |
| BCN5055 | alpha-Amyrin palmitate |
| 1. alpha-Amyrin palmitate is antiarthritic in the adjuvant model of arthritis in rats. 2. alpha-Amyrin palmitate is a potent non-competitive inhibitor of chymotrypsin (Ki=6 microM). 3. alpha Amyrin palmitate shows weak cytotoxicity against the A2780 human ovarian cancer cell line. | |
