Products with Inhibitors bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN4883 | Isodiospyrin |
| 1. Isodiospyrin is a novel human DNA topoisomerase I inhibitor, it exhibits cytotoxic activity to tumor cell lines. 2. Isodiospyrin has antibacterial activity, the minimum inhibitory concentrations (MICs) against Gram-positive bacteria ranged from 0.78 to 50 microg/mL. 3. Isodiospyrin shows high antifungal activity against P. obscurans at 30uM with 81.4% growth inhibition, and moderate activity against P. viticola (36.6%). | |
| BCN4887 | 13(18)-Oleanen-3-one |
| 1. δ-Amyrone(13(18)-Oleanen-3-one), a specific inhibitor of cyclooxygenase-2, possesses anti-inflammatory effects, which may be relevant to the regulation of COX-2. 2. δ-Amyrone has protective activity on LPS-induced endotoxic shock, which is attributed to reducing NO production and mediating the pro-inflammatory cytokines, inhibited NF-κB expression. 3. δ-Amyrone exerts its protective effect on experimental gastric ulcer by inhibiting NF-κB signaling pathways, which subsequently reduces overproduction of the inducible enzymes iNOS and suppresses the release of the inflammatory factors TNF-α, IL-6 and NO. | |
| BCN4899 | Coniferaldehyde |
| 1. Coniferaldehyde exerts anti-inflammatory properties by inducing heme oxygenase-1(HO-1), it inhibits LPS-induced apoptosis through the PKC α/β II/Nrf-2/HO-1 dependent pathway in RAW264.7 macrophage cells. 2. Coniferaldehyde can significantly inhibit the growth of viability of strains of Oenococcus oeni . | |
| BCN4900 | Sinapaldehyde |
| 1. Sinapaldehyde has effects against 65 strains of Candida . 2. The reaction of sinapaldehyde and methylpyranoanthocyanin can obtain a new bluish pigment. 3. Sinapaldehyde inhibits prostaglandin synthetase in a dose-dependent way, it dose-dependently inhibits ethyl phenylpropiolate-induced edema of the rat ear, and can inhibit electrically induced contractions of the guinea pig ileum in a dose-dependent way. | |
| BCN4922 | Taxiphyllin |
| 1. Taxiphyllin can inhibit tyrosinase activity in vitro significantly and is a potent tyrosinase inhibitor. 2. Taxiphyllin displays mild antibacterial activity against Staphylococcus aureus. | |
