Products with Antiviral bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN5487 | Crategolic acid |
| Crategolic acid(Maslinic acid) has neuroprotective, anti-inflammatory, anti- osteoporosis, cytotoxic and antiviral activities, it suppresses RANKL-induced osteoclastogenesis through NF-κB and MAPK/AP-1 signaling pathways , and has beneficial effects on hypoxic neurons by suppressing iNOS activation.Crategolic acid as a feed additive to stimulate growth and hepatic protein-turnover rates in rainbow trout ( Onchorhynchus mykiss ). | |
| BCN5500 | Betulonic acid |
| Betulonic acid has anti-cancer , anti-HIV,hepatoprotective and anti-inflammatory activities, it has antiviral activity against herpes simplex virus, it also suppresses ECHO 6 virus reproduction. Betulonic acid derivatives have a promising cytostatic activity in vitro and could be used as potential leads for the development of new type of anti-cancer agents. | |
| BCN5524 | Betulinic acid |
| Betulinic acid is a natural pentacyclic triterpenoid, acts as a eukaryotic topoisomerase I inhibitor, with an IC50 of 5 μM, and possesses anti-HIV, anti-malarial, immunomodulatory, anti-inflammatory and anti-tumor properties.Betulinic acid is a selective inducer of apoptosis in tumor cells, it inhibits activation of NF-kappaB and NF-kappaB-regulated gene expression induced by carcinogens and inflammatory stimuli. | |
| BCN5528 | Betulin |
| Betulin (Trochol), is a sterol regulatory element-binding protein (SREBP) inhibitor with an IC50 of 14.5 μM in K562 cell line. Betulin has hypoglycemic, antineoplastic, anti-HIV, antimalarial and anti-inflammatory activities. Betulin can improve hyperlipidemia and insulin resistance and reduce atherosclerotic plaques. Betulin inhibits pro-inflammatory cytokines expression and NF-κB signaling activation through STAT3 signaling, it is associated with activation of AMP kinase and inhibition of mTOR/p70S6K/pS6 signaling in these cells. | |
| BCN5538 | Isotetrandrine |
| 1. Isotetrandrine is a small molecule inhibitor, on various aspects of LPS-induced inflammation in vitro and in vivo. 2. Isotetrandrine dose-dependently suppresses the severity of LPS-induced ALI by inactivation of MAPK and NF-κB, which may involve the inhibition of tissue oxidative injury and pulmonary inflammatory process. | |
