Products with Antiviral bioactivity

Cat.No. Product Name
BCN6715 Yadanzioside I
1. Yadanzioside I shows strong antiviral activity.
BCN6721 Yadanziolide A
1. Yadanziolide A shows strong antiviral activity.
BCN6723 Xanthopurpurin
1. Xanthopurpurin may can effectively inhibit rotavirus multiplication by promoting virus-induced apoptosis in MA-104 cells. 2. Xanthopurpurin shows mainly strong inhibition of collagen-induced platelet aggregation.
BCN6794 Harringtonine
Harringtonine , an anticancer drug with high chemotherapeutic efficiency to human chronic granulocytic/myelomonocytic leukemia, has been reported to rapidly induce apoptosis in HL-60 cells in a wide scope/range of dosage by investigators from our lab and others. Harringtonine exerts its antiviral effects by inhibiting Chikungunya virus (CHIKV) viral protein synthesis.
BCN6796 Mosloflavone
1. Mosloflavanone is an antifungal and radical scavenging 2-hydroxyflavanone. 2. Mosloflavone possesses strong anti-EV71 activity and decreased the formation of visible cytopathic effects, it also inhibits virus replication during the initial stage of virus infection, and inhibits viral VP2 protein expression, thereby inhibiting viral capsid protein synthesis. 3. Mosloflavone can significantly prolong the survival time of hypoxic mice. 4. Mosloflavone shows promising anti-inflammatory activity via inhibition of TNF-α and IL-1β with IC50 values of 16.4 uM and 6.4 uM, respectively; it shows dose-dependent inhibition of TNF-α, IL-1β and iNOS levels in the supernatant of mouse macrophage cell line J774A. 5. Mosloflavone can be used as a starting point to discover lead structures for treatment of inflammatory and immunomodulatory diseases.

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