Products with Antiviral Bioactivity

Explore BioCrick products associated with Antiviral biological activity, including catalog numbers, product names and available bioactivity information.

Cat. No.	Product Name
BCN5735	Andrographolide
Andrographolide is an antiinflammatory, antiviral, anti-cancer , hepatoprotective, antithrombotic, hypotensive and antiatherosclerotic drug, it can cure hyperpigmentation disorders. Andrographolide protects against chemical-induced oxidative damage by up-regulating the gene transcription and activity of antioxidant enzymes in various tissues.Andrographolide has potential as a leading compound in the prevention or treatment of obesity and insulin resistance, can ameliorate lipid metabolism and improve glucose use in mice with HFD-induced obesity.
BCN5743	Myriceric acid B
1. Myriceric acid B is a potent HIV-1 entry inhibitor targeting gp41 and can serve as a lead compound for developing novel anti-HIV-1 drug. 2. Myriceric acid B scavenges DPPH free radicals with IC50 value of 21.8 uM, it inhibits aromatase activity with IC50 value of 6.8 uM, it also exhibits cytotoxic activity towards the MOLT-3 cell line with IC50 values of 3.9 uM.
BCN5746	beta-Amyrin
1. alpha- and beta-Amyrin have hepatoprotective potential against toxic liver injury, the diminution in oxidative stress and toxic metabolite formation as likely mechanisms involved in its hepatoprotection. 2. alpha- and beta-Amyrin have antinociceptive properties in inflammatory models of pain, the mechanisms involved in their action are not completely understood but seem to involve the inhibition of protein kinase A- and protein kinase C-sensitive pathways. 3. alpha- and beta-Amyrin have anti-inflammatory potential, they retard acute inflammation in rat model of periodontitis and warrant further study on its efficacy to prevent chronic periodontitis-associated bone loss. 4. alpha- and beta-Amyrin mixture has gastro-protective activity, the mechanism involves at least in part the activation of capsaicin-sensitive primary afferent neurons. 5. alpha- and beta-Amyrin mixture has sedative and anxiolytic effects, the mechanism may involve an action on benzodiazepine-type receptors, and also an antidepressant effect where noradrenergic mechanisms will probably play a role. 6. Beta-Amyrin can enhance the total sleeping behavior in pentobarbital-induced sleeping model via the activation of GABAergic neurotransmitter system through GABA content in the brain. 7. beta-Amyrin has antiviral activity.
BCN5757	Eichlerianic acid
1. Eichlerianic acid shows weak cytotoxicity (IC50 6.87 to >40 μM) against human cancer cell (HL-60, SMMC-7721, A-549, MCF-7 and SW480). 2. Eichlerianic acid is a trypanocidal compound with an IC50 value of 10 mg/mL. 3. Eichlerianic acid may have antiviral activity against Herpes simplex virus types I and II in vitro.
BCN5767	Penduletin
1. Penduletin shows anti- tumor cells activity. 2. Penduletin significantly reduces TGF-β1 production. 3. Penduletin has strong activity in vitro against EV71 with low cytotoxicity. 4. Penduletin inhibits growth of the Gram-negative pathogen neisseria gonorrhoeae. 5. Penduletin may have anti-inflammatory activity, it can partially inhibit synovial phospholipase A2 activity.

Antiviral Bioactivity Products