Products with Alpha-glucosidase inhibitors bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN5862 | 3alpha-Akebonoic acid |
| 1. 3α-Akebonoic acid shows interesting in vitro growth inhibitory activity against human tumor A549 and HeLa cell lines, it also shows significant in vitro α-glucosidase inhibitory activity. 2. 3α-Akebonoic acid can interfer with presenilin-1 (PS1)/ β-site APP-cleaving enzyme 1 (BACE1) interaction and reduces Aβ production, the chemical interference of PS1/BACE1 interaction is a promising strategy for Alzheimer’s disease therapeutics. | |
| BCN5895 | Glycitin |
| Glycitin has antibacterial, antiviral, anti-obese,anti-diabetic and estrogenic activities and may exert preventative effects on alcoholism, osteonecrosis,cardiovascular and cerebrovascular diseases and some types of cancer. It has a protective effect on skin aging by inhibiting of MMP-1 and increasing of collagen through ERK/JNK/P38 down-regulation, shows good inhibitory effect on α-glucosidase with IC50 of 0.5646 mg/mL. | |
| BCN6072 | Balanophonin |
| Balanophonin shows potent α-glucosidase inhibitory activity, it has antioxidant, and anti-cancer activities. (±)-Balanophonin shows significant antibacterial activity against cariogenic oral streptococci, Streptococcus mutans and S. sobrinus. | |
| BCN6486 | 3,7-Di-O-methylquercetin |
| 1. 3,7-Di-O-methylquercetin shows α-glucosidase inhibition. | |
| BCN6660 | Taxoquinone |
| 1. Taxoquinone shows significant and concentration-dependent antioxidant and free radical scavenging activities of DPPH, nitric oxide, superoxide and hydroxyl free radicals by 78.83%, 72.42%, 72.99% and 85.04%, as compared to standard compounds ascorbic acid (81.69%, 74.62%, 73% and 73.79%). 2. Taxoquinone at the concentration range of 100-3,000 ug/mL and 200-1,000 ug/mL shows potent efficacy on inhibiting α-glucosidase and tyrosinase enzymes by 9.24-51.32% and 11.14-52.32%, respectively; suggests that taxoquinone could as a novel candidate in food and medicine industry as a natural alternative medicine to prevent diabetes mellitus type-2 related disorders and as a depigmentation agent. 3. Taxoquinone (100 ug/disc) displays potential anticandidal effect against Candia albicans. 4. Taxoquinone has strong antibacterial effect, it could be used as a promising antibacterial agent in food industry to inhibit the growth of certain important foodborne pathogens. | |
