Products with Alpha-glucosidase inhibitors bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN5634 | 7,4'-Di-O-methylapigenin |
| 1. Apigenin 7, 4'-dimethyl ether (7,4'-Di-O-methylapigenin) can inhibit α-glucosidase and α-amylase enzymes and enhance 2-NBDG uptake in L6 cells, it has hypolipidemic effect on mouse pre-adipocyte (3T3L1) cell lines. | |
| BCN5666 | 3-Epicorosolic acid |
| 1. 3-Epicorosolic acid has a potent inhibitory effect on Epstein-Barr virus early antigen (EBV-EA) induction. 2. 3-Epicorosolic acid shows both potent α-glucosidase and protein tyrosine phosphatase 1B (PTP1B) inhibitory activities with IC50 values of 30.18 and 4.08 μg/ml respectively. 3. 3-Epicorosolic acid shows mixed type inhibition against PTP1B, while it shows uncompetitive inhibition against α-glucosidase; suggests that it has potential antidiabetic activity. 4. 3-Epicorosolic acid possesses the ability to inhibit the expression of one or more inflammatory genes induced by 12-O-tetradecanoylphorbol-13 acetate in mouse skin, it has potential anti-inflammatory activities as well as cancer chemopreventive activity. | |
| BCN5720 | 15-Hydroxydehydroabietic acid |
| 1. 15-Hydroxydehydroabietic acid exhibits a promising alpha-glucosidase inhibitory activity, it also shows significant antibacterial activities. | |
| BCN5779 | Carpachromene |
| 1. Carpachromene blocks protein expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) in LPS-stimulated macrophages, it could be a potential anti-inflammatory agent. 2. Carpachromene exhibits significant cytotoxicity against HepG2, PLC/PRF/5 and Raji cancer cell lines in vitro. 3. Carpachromene shows significant α-glucosidase inhibitory activity. | |
| BCN5859 | Ganoderol B |
| Ganoderol B is a potent α-glucosidase and angiotensin-converting enzyme inhibitor, with an IC(50) of α-glucosidase is 119.8 uM. It may be useful in prostate cancer and benign prostatic hyperplasia (BPH) therapy through suppressing the function of androgen and its receptor. | |
