Products with Alpha-glucosidase inhibitors bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN3849 | Irigenin |
| Irigenin, an α-glucosidase inhibitor, which has anti-inflammatory, anti-cancer, and anti-metastatic effects. Irigenin can inhibit the expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase (COX)-2 proteins and mRNAs without an appreciable cytotoxic effect. Irigenin displays moderate activity as inducers of NAD(P)H:quinone reductase (QR) in cultured mouse Hepa 1c1c7 cells. | |
| BCN3886 | Gitogenin |
| 1. Gitogenin, tigogenin, and solasodine are novel selective inhibitors of UGT1A4, and do not inhibit the activities of major human CYP isoforms. 2. Gitogenin and (25S)-5α-furastan-3β,22,26-triol are the inhibitors of enzyme α-glucosidase with IC50 values of 37.2±0.18 and 33.5±0.22 uM, respectively. 3. Gitogenin shows moderate stimulation of release activity on growth hormone from rat pituitary cells. | |
| BCN4179 | beta-Amyrone |
| 1. beta-Amyrone has antifungal activity. 2. beta-Amyrone exhibits anti-α-glucosidase inhibitory activity and moderate anti- acetylcholinesterase (AChE) activity. 3. beta-Amyrone shows a moderate activity against Chikungunya virus replication (EC50 =86 uM). | |
| BCN4181 | Torachrysone 8-O-glucoside |
| 1. Torachryson-8-O-glucoside shows alpha-glucosidase inhibitory activities, it may be used for the management of type 2 diabetes. | |
| BCN4509 | Guajadial |
| 1. Guajadial, psidial A and psiguadials A and B can reduce tumor growth and stimulate uterus proliferation, suggest that they may act as Selective Estrogen Receptors Modulators (SERMs), therefore holding significant potential for anticancer therapy. 2. Guajadial shows α-glucosidase inhibitory activities significantly and its activity was better than that of Acarbose. 3. Guajadial exhibits potent inhibitory effects on the growth of human hepatoma cells. | |
