Schizophrenia Research

Schizophrenia is a chronic, debilitating mental disorder affecting 1-2% of the global population. Symptoms are split into two types; 'positive' symptoms, including delusions and hallucinations, and 'negative' symptoms, including anhedonia and lack of motivation. Studies suggest that genetics, early environment, neurobiology, psychological and social processes are important contributory factors; some recreational and prescription drugs appear to cause or worsen symptoms. Several neurobiological alterations in brain structure, physiology and neurochemistry have been documented, along with an ever-increasing list of susceptibility genes.

Schizophrenia Research Products Targets

Products for Schizophrenia Research - Page 63

  1. Cat.No. Product Name Information/Activity
  2. BCC7347 LY 456236 hydrochloride 338736-46-2 LY 456236 hydrochloride chemical structure
  3. BCC7281 3-MATIDA 518357-51-2 3-MATIDA chemical structure
  4. BCC7756 (RS)-MCPG disodium salt 1303994-09-3 (RS)-MCPG disodium salt chemical structure
  5. BCC6610 (RS)-MCPG (RS)-MCPG (alpha-MCPG) is a competitive and selective group I/group II metabotropic glutamate receptor (mGluR) antagonist. (RS)-MCPG blocks theta-burst stimulation (TBS)-induced shifts in both juvenile and neonatal rat hippocampal neurons. (RS)-MCPG chemical structure
  6. BCC6611 (S)-MCPG (S)-MCPG is the active isomer of (RS)-MCPG (Cat. (S)-MCPG chemical structure
  7. BCC1777 MPEP Hydrochloride MPEP hydrochloride is a potent and highly selective non-competitive antagonist at the mGlu5 receptor subtype with IC50 of 36 nM. MPEP Hydrochloride chemical structure
  8. BCC1780 MTEP hydrochloride MTEP hydrochloride is a potent, selective and non-competitive mGlu5 antagonist with an IC50 of 5 nM and a Ki of 16 nM. MTEP hydrochloride produces antiparkinsonian-like effects. MTEP hydrochloride chemical structure
  9. BCC6119 NPS 2390 226878-01-9 NPS 2390 chemical structure
  10. BCC6895 PHCCC PHCCC is a Group I metabotropic glutamate receptor antagonist with EC 50 of 6 uM and a positive allosteric modulator of mGluR4. Also as a potent to antagonism for mGluR2 and mGluR8. PHCCC chemical structure
  11. BCC6971 SIB 1757 31993-01-8 SIB 1757 chemical structure

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