Parkinson's Disease Research

Parkinson's disease (PD) is a degenerative disease of the central nervous system that often impairs motor skills, speech, and other functions. Symptoms of the disease include resting tremor, bradykinesia and rigidity. The primary symptoms are the result of decreased stimulation of the motor cortex by the basal ganglia, normally caused by the insufficient formation and action of dopamine, which is produced in the dopaminergic neurons of the brain. Symptoms of the disease appear once 50-80% of dopamine neurons have died. Parkinson's disease is both chronic and progressive.

Parkinson's Disease Research Products Targets

Products for Parkinson's Disease Research - Page 25

  1. Cat.No. Product Name Information/Activity
  2. BCC7240 PSB 36 524944-72-7 PSB 36 chemical structure
  3. BCC7656 SLV 320 Derenofylline (SLV 320) is a potent, selective and orally active adenosine A1 receptor antagonist, with Ki values of 1 nM, 200 nM and 398 nM for human A1, A3 and A2A receptors respectively. Derenofylline suppresses cardiac fibrosis and attenuates albuminuria without affecting blood pressure in rats. SLV 320 chemical structure
  4. BCC7032 PD 81723 132861-87-1 PD 81723 chemical structure
  5. BCC4316 CGS 21680 HCl CGS 21680 Hydrochloride is a selective adenosine A2A receptor agonist with a Ki of 27 nM. CGS 21680 HCl chemical structure
  6. BCC7163 CV 1808 53296-10-9 CV 1808 chemical structure
  7. BCC6237 LUF 5834 333962-91-7 LUF 5834 chemical structure
  8. BCC7815 ANR 94 Adenosine A<sub>2A </sub>antagonist ANR 94 chemical structure
  9. BCC3798 Istradefylline (KW-6002) Istradefylline is a very potent, selective and orally active adenosine A2A receptor antagonist with Ki of 2.2 nM in experimental models of Parkinson's disease. Istradefylline (KW-6002) chemical structure
  10. BCC7977 Lu AA 47070 913842-25-8 Lu AA 47070 chemical structure
  11. BCC7372 SCH 442416 316173-57-6 SCH 442416 chemical structure

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