Huntington's Disease Research
Huntington's disease is a neurodegenerative disease characterized by cognitive decline and motor dysfunction. It is a genetic disorder which results in the production of mutant huntingtin protein (mHtt). This protein aggregates in the cell cytoplasm and nucleus, affecting cellular function.
Huntington's Disease Research Products Targets
- Adenosine A2A Receptor (11)
- Caspase (9)
- Ubiquitin-activating Enzyme E1 (3)
- Ubiquitin E2 Conjugating Enzyme (3)
- Ubiquitin E3 Ligase (10)
- Deubiquitinating Enzyme (12)
- Hsp90 (10)
- Hsp70 (4)
- Glutamate (Metabotropic) Group III Receptor (26)
- Glutamate (Metabotropic) Group II Receptor (33)
- Glutamate (Metabotropic) Group I Receptor (54)
- Vesicular Monoamine Transporter (4)
- Sir 2-like Family Deacetylase (9)
- Post-Translational Modification (11)
- NMDA Receptor (87)
- Kainate Receptor (22)
- IP3 Receptor (2)
- ERK (6)
- D2 Receptor (14)
- D1 and D5 Receptor (16)
- Calpain (7)
- Trk Receptor (13)
- Autophagy (44)
- Antioxidant (19)
- Glutamate Transporter (18)
- Dopamine Transporter (20)
- Cathepsin (9)
- Mitochondrial Permeability Transition Pore (3)
- Proteasome (5)
- Histone Deacetylase (19)
- Histone Acetyltransferase (4)
Products for Huntington's Disease Research - Page 40
- Cat.No. Product Name Information/Activity
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BCC6632
Spaglumic acid
Spaglumic Acid is a neuropeptide found in millimolar concentrations in brain.
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BCC6925
(RS)-APICA
170847-18-4
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BCC6871
EGLU
EGLU ((2S)-α-Ethylglutamic acid; (2S)-α-EGLU) is a potent and competitive mGluR-2 receptor antagonist. EGLU interacts with (lS,3S)-ACPD-sensitive site with a Kd value of 66 μM. EGLU is an antidepressant agent.
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BCC1724
LY341495
LY341495 is a metabotropic glutamate receptor (mGluR) antagonist with IC50s of 2.9 nM, 10 nM, 170 nM for mGluR-2, mGluR-3, mGluR-8, respectively.
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BCC6819
MSPG
169209-64-7
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BCC6820
MTPG
169209-66-9
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BCC7513
Ro 64-5229
246852-46-0
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BCC7849
BINA
Biphenylindanone A (BINA) is a selective human mGluR2 (hmGluR2) potentiator for the treatment of many neurological disorders.
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BCC7824
CBiPES hydrochloride
856702-40-4
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BCC7985
LY 2389575 hydrochloride
885104-09-6


