Huntington's Disease Research

Huntington's disease is a neurodegenerative disease characterized by cognitive decline and motor dysfunction. It is a genetic disorder which results in the production of mutant huntingtin protein (mHtt). This protein aggregates in the cell cytoplasm and nucleus, affecting cellular function.

Huntington's Disease Research Products Targets

Products for Huntington's Disease Research - Page 28

Cat.No. Product Name Information/Activity
BCC5859 Norketamine hydrochloride 79499-59-5
BCC7895 NPEC-caged-D-AP5 1416943-27-5
BCC5644 Pentamidine isethionate Pentamidine isethionate (MP-601205 isethionate) is an antimicrobial agent and interferes with DNA biosynthetics. Pentamidine isethionate inhibits parasite Leishmania infantum with an IC50 of 2.5 μM. Pentamidine isethionate is a potent and selective protein tyrosine phosphatases (PTPases) and phosphatase of regenerating liver (PRL) inhibitor. Pentamidine isethionate has the potential for Gambian trypanosomiasis, antimony-resistant leishmaniasis, and Pneumocystis carinii pneumonia treatment. Antitumor and antibacterial activities.
BCC7308 PMPA (NMDA antagonist) 113919-36-1
BCC5918 PPDA 684283-16-7
BCC7309 PPPA 113190-92-4
BCC6292 QNZ 46 QNZ46 is a NR2C/NR2D-selective NMDA receptor non-competitive antagonist (IC50 values are 3, 6, 229, and >300, >300 μM for NR2D, NR2C, NR2A, NR2B, and GluR1, respectively).
BCC7129 Remacemide hydrochloride 111686-79-4
BCC7234 Ro 04-5595 hydrochloride 64047-73-0
BCC4159 Ro 25-6981 Maleate Ro 25-6981 Maleate is a potent and selective activity-dependent blocker of NMDA receptors containing the NR2B subunit.