Endocrinology Research
Endocrinology is the study of hormones, their signaling pathways, and the diseases associated with them. The endocrine system is one of two mechanisms in the human body that is responsible for regulating and integrating the function of cells, the other being the nervous system.
Endocrinology Research Products Areas
Products for Endocrinology Research - Page 14
- Cat.No. Product Name Information/Activity
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BCC6772
2-Iodomelatonin
2-Iodomelatonin is a potent agonist of melatonin receptor 1 (MT1) with a Ki value of 28 pM, it is more 5-fold selective for MT1 over MT2. 2-iodomelatonin can be used to identify, characterize and localize melatonin binding sites in the brain and peripheral tissues.
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BCN2196
Melatonin
Melatonin is a hormone made by the pineal gland that can activates melatonin receptor. Melatonin plays a role in sleep and possesses important antioxidative and anti-inflammatory properties. Melatonin is a novel selective ATF-6 inhibitor and induces human hepatoma cell apoptosis through COX-2 downregulation.
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BCC6901
8-M-PDOT
8-M-PDOT (AH-002) is a selective melatonin MT2 receptor agonist. 8-M-PDOT is 5.2-fold selective for MT2 over MT1 receptors. 8-M-PDOT binds human recombinant MT2 and MT2 receptors with pKi values of 8.23 and 8.95 respectively. 8-M-PDOT has anxiolytic-like activity.
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BCC6748
2-Phenylmelatonin
151889-03-1
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BCC6973
DH 97
220339-00-4
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BCC6826
Luzindole
Luzindole (N-0774) is a selective melatonin receptor antagonist. Luzindole preferentially targets MT2 (Mel1b) over MT1 (Mel1a) with Ki values of 10.2 and 158 nM for human MT2 and MT1, respectively. Luzindole suppresses experimental autoimmune encephalomyelitis (EAE), and exerts antidepressant-like activity.
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BCC2505
Prazosin HCl
Prazosin hydrochloride is an alpha-adrenergic blocker and is a sympatholytic drug used to treat high blood pressure and anxiety, PTSD, and panic disorder.
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BCC6836
GR 135531
190277-13-5
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BCN2203
Corticosterone
Corticosterone is an adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid.
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BCC4395
Benidipine HCl
Benidipine hydrochloride is a dihydropyridine calcium channel blocker for the treatment of high blood pressure (hypertension).
