Cardiovascular System Research

The cardiovascular, or circulatory, system is a closed elastic circuit consisting of the heart, blood vessels (arteries, capillaries and veins) and the blood. The primary function is to pump oxygenated blood to the tissues throughout the body and reabsorb waste carbon dioxide for its removal. This function is performed by the use of pulmonary and systemic circulation.

Cardiovascular System Research Products Areas

Products for Cardiovascular System Research - Page 67

  1. Cat.No. Product Name Information/Activity
  2. BCC4677 Mexiletine HCl Mexiletine hydrochloride (KOE-1173 hydrochloride), a Class IB antianhythmic, is a non-selective voltage-gated sodium channel blocker. Mexiletine HCl chemical structure
  3. BCC5077 Oxcarbazepine Oxcarbazepine (GP 47680) inhibits the binding of [3H]BTX to sodium channels with IC50 of 160 μM and also inhibits the influx of 22Na+ into rat brain synaptosomes with IC50 about 100 μM. Oxcarbazepine chemical structure
  4. BCC6328 Phrixotoxin 3 880886-00-0 Phrixotoxin 3 chemical structure
  5. BCC6103 ProTx II ProTx II is a selective blocker of Nav1.7 sodium channels with an IC50 of 0.3 nM, and is at least 100-fold selective for Nav1.7 over other sodium channel subtypes. ProTx-II inhibits sodium channels by decreasing channel conductance and shifting activation to more positive potentials and blocks action potential propagation in nociceptors. ProTx II chemical structure
  6. BCC6906 QX 222 5369-00-6 QX 222 chemical structure
  7. BCC6889 QX 314 bromide QX-314 bromide is a membrane-impermeable permanently charged sodium channel blocker. QX 314 bromide chemical structure
  8. BCC7326 QX 314 chloride QX-314 chloride is a membrane-impermeable permanently charged sodium channel blocker. QX 314 chloride chemical structure
  9. BCC7844 Ralfinamide mesylate Ralfinamide mesylate (FCE-26742A mesylate) is an orally available Na+ channel blocker derived from α-aminoamide, with function of suppressing pain. Ralfinamide mesylate chemical structure
  10. BCC7847 Sipatrigine Sipatrigine, a neuroprotective agent, is a glutamate release inhibitor, voltage-dependent sodium channel and calcium channel inhibitor, penetrating the central nervous system. Has potential to treat focal cerebral ischemia and stroke. Sipatrigine chemical structure
  11. BCC6179 TC-N 1752 1211866-85-1 TC-N 1752 chemical structure

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