Cardiovascular System Research
The cardiovascular, or circulatory, system is a closed elastic circuit consisting of the heart, blood vessels (arteries, capillaries and veins) and the blood. The primary function is to pump oxygenated blood to the tissues throughout the body and reabsorb waste carbon dioxide for its removal. This function is performed by the use of pulmonary and systemic circulation.
Cardiovascular System Research Products Areas
Products for Cardiovascular System Research - Page 64
- Cat.No. Product Name Information/Activity
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BCC7182
E-4031 dihydrochloride
E-4031 is a class III antiarrhythmic agent which selectively blocks hERG potassium channel.
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BCC7806
JNJ 303
JNJ 303 is a potent IKs blocker with an IC50 value of 64 nM. JNJ 303 does not have any effects on other cardiac channels at concentrations of 3.3 μM for INa, Ica, Ito, and IKr. JNJ 303 induces QT-prolongations and causes unprovoked torsades de pointes (TdP).
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BCC1682
KN-92 phosphate
KN-92 phosphate is an inactive derivative of KN-93.
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BCC1683
KN-93
CaM kinase II inhibitor; also K<sup>+</sup> channel blocker (K<sub>V</sub>),KN-93 is a novel membrane-permeant synthetic inhibitor of purified neuronal <b>CaMK-II</b>, with K<sub>i</sub> of 370 nM.
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BCC7231
Linopirdine dihydrochloride
113168-57-3
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BCC7709
Margatoxin
Margatoxin, an alpha-KTx scorpion toxin, is a high affinity inhibitor of Kv1.3 (Kd=11.7 pM). Margatoxin inhibits the Kv1.2 (Kd=6.4 pM) and Kv1.1 (Kd=4.2 nM). Margatoxin, a 39 amino-acid-long peptide, is isolated from the venom of the scorpion Centruroides margaritatus and widely used in ion channel research.
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BCC7927
Psora 4
Potent K<sub>V</sub>1.3 channel blocker
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BCC6044
RuBi-4AP
851956-02-0
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BCC5990
ShK-Dap22
220384-25-8
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BCC7554
Tetraethylammonium chloride
Non-selective K<sup>+</sup> channel blocker
