Hypertension Research

Hypertension is defined as a chronic elevation in blood pressure with a systolic pressure over 140 mmHg and a diastolic pressure over 90 mmHg.The majority of hypertension is primary - that is, an increase in blood pressure with no underlying cause - yet pathologies that affect the kidney or endocrine system may also trigger hypertension. This is known as secondary hypertension. The exact mechanism of primary hypertension is yet to be elucidated, though dysfunctions in mechanisms that regulate vascular tone, both directly and indirectly, have been identified as having a major influence on hypertension.

Hypertension Research Products Targets

Products for Hypertension Research - Page 9

  1. Cat.No. Product Name Information/Activity
  2. BCC7626 Canrenone Canrenone (Aldadiene; SC9376; SC14266) is an aldosterone antagonist extensively used as a diuretic agent. Canrenone chemical structure
  3. BCC3776 Epleremone Eplerenone is an aldosterone antagonist with an IC50 of 0.36 μM. Epleremone chemical structure
  4. BCC7531 RU 26752 76676-33-0 RU 26752 chemical structure
  5. BCC7146 RU 28318, potassium salt 76676-34-1 RU 28318, potassium salt chemical structure
  6. BCC4366 Spironolactone Spironolactone is a potent antagonist of the androgen receptor. Spironolactone chemical structure
  7. BCC5843 Atrial natriuretic factor (1-28) (rat) Atrial Natriuretic Peptide (ANP) (1-28), rat is a major circulating form of ANP in rats, potently inhibits Angiotensin II (Ang II)-stimulated endothelin-1 secretion in a concentration-dependent manner. Atrial natriuretic factor (1-28) (rat) chemical structure
  8. BCC5839 Atrial natriuretic factor (1-28) (human, porcine) 91917-63-4 Atrial natriuretic factor (1-28) (human, porcine) chemical structure
  9. BCC6034 Brain natriuretic peptide (1-32) (human) Nesiritide (Brain Natriuretic Peptide-32 human) is an agonist of natriuretic peptide receptors (NPRs), with Kd values of 7.3 and 13 pM for NPR-A and NPR-C, respectively. Brain natriuretic peptide (1-32) (human) chemical structure
  10. BCC6033 C-type natriuretic peptide (1-22) (human, rat, swine) C-Type Natriuretic Peptide (CNP) (1-22), human is the 1-22 fragment of C-Type Natriuretic Peptide. C-type natriuretic peptide is natriuretic peptide family peptide that is involved in the maintenance of electrolyte-fluid balance and vascular tone. C-type natriuretic peptide (1-22) (human, rat, swine) chemical structure
  11. BCC6055 Neuromedin S (rat) 843782-19-4 Neuromedin S (rat) chemical structure

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