Hypertension Research

Hypertension is defined as a chronic elevation in blood pressure with a systolic pressure over 140 mmHg and a diastolic pressure over 90 mmHg.The majority of hypertension is primary - that is, an increase in blood pressure with no underlying cause - yet pathologies that affect the kidney or endocrine system may also trigger hypertension. This is known as secondary hypertension. The exact mechanism of primary hypertension is yet to be elucidated, though dysfunctions in mechanisms that regulate vascular tone, both directly and indirectly, have been identified as having a major influence on hypertension.

Hypertension Research Products Targets

Products for Hypertension Research - Page 17

  1. Cat.No. Product Name Information/Activity
  2. BCC7843 16,16-Dimethyl Prostaglandin E2 16,16-Dimethyl prostaglandin E2 (16,16-dimethyl PGE2) is an orally active vertebrate Hematopoietic stem cells (HSCs) homeostasis critical regulator. 16,16-Dimethyl prostaglandin E2 can act through EP2/EP4 and has an interaction with the Wnt pathway. 16,16-Dimethyl Prostaglandin E2 chemical structure
  3. BCC7534 Epoprostenol Epoprostenol sodium (Prostaglandin I2 (sodium salt)), the synthetic form of the natural prostaglandin derivative prostacyclin (prostaglandin I2), is registered worldwide for the treatment of Pulmonary arterial hypertension (PAH). Epoprostenol sodium is used in pulmonary hypertension and transplantation as a potent inhibitor of platelet aggregation. Epoprostenol chemical structure
  4. BCC7247 Iloprost Iloprost (ZK 36374) is a synthetic analogue of prostacyclin PGI2. Iloprost chemical structure
  5. BCC5240 Misoprostol 59122-46-2 Misoprostol chemical structure
  6. BCC7316 Prostaglandin E2 Prostaglandin E2 is a hormone-like substance that participate in a wide range of body functions such as the contraction and relaxation of smooth muscle, the dilation and constriction of blood vessels, control of blood pressure, and modulation of inflammation. Prostaglandin E2 chemical structure
  7. BCC7889 Prostaglandin F2α Dinoprost tromethamine salt is a naturally occurring prostaglandin used in medicine to induce labor and as an abortifacient. Prostaglandin F2α chemical structure
  8. BCC7661 NS 304 Selexipag (NS-304) is an orally available and potent agonist for the Prostacyclin (PGI2) receptor (IP receptor). NS 304 chemical structure
  9. BCC7547 Sulprostone 60325-46-4 Sulprostone chemical structure
  10. BCC7853 TCS 2510 346673-06-1 TCS 2510 chemical structure
  11. BCC7207 U 46619 U-46619 (9,11-Methanoepoxy PGH2) is a stable analogue of thromboxane A2 (TXA2) and acts as a potent TXA2 agonist. U 46619 chemical structure

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