Intracellular Signaling

Cell signaling (cell signalling in British English) is part of any communication process that governs basic activities of cells and coordinates all cell actions. The ability of cells to perceive and correctly respond to their microenvironment is the basis of development, tissue repair, and immunity, as well as normal tissue homeostasis. Errors in signaling interactions and cellular information processing are responsible for diseases such as cancer, autoimmunity, and diabetes. By understanding cell signaling, diseases may be treated more effectively and, theoretically, artificial tissues may be created.

Intracellular Signaling Products Targets

Products for Intracellular Signaling - Page 25

  1. Cat.No. Product Name Information/Activity
  2. BCC2540 Tazarotene Tazarotene (AGN 190168) is a selective retinoic acid receptor (RAR) agonist for the treatment of plaque psoriasis and acne vulgaris. Tazarotene chemical structure
  3. BCC4874 TTNPB (Arotinoid Acid) TTNPB is a highly potent RAR agonist. Competitive binding assays using human RARs yield IC50s of α=5.1 nM, β= 4.5 nM, and γ=9.3 nM, respectively. TTNPB (Arotinoid Acid) chemical structure
  4. BCC7740 BMS 195614 253310-42-8 BMS 195614 chemical structure
  5. BCC7697 BMS 493 BMS493 is an inverse pan-retinoic acid receptor (RAR) agonist. BMS493 increases nuclear corepressor interaction with RARs. BMS493 also could prevent retinoic acid-induced differentiation. BMS 493 chemical structure
  6. BCC7778 CD 2665 CD2665 is a selective RAR-beta/gamma antagonist, with Ki values of 110 nM, 306 nM for RARγ and RARβ, respectively. CD 2665 chemical structure
  7. BCC7783 ER 50891 187400-85-7 ER 50891 chemical structure
  8. BCC7782 MM 11253 345952-44-5 MM 11253 chemical structure
  9. BCC7679 BMS 453 166977-43-1 BMS 453 chemical structure
  10. BCC6097 EC 23 EC23 (AGN 190205) is a stable synthetic retinoid analogue and induces neuronal differentiation. EC 23 chemical structure
  11. BCC1572 Fenretinide Synthetic retinoid; antiproliferative and antioxidant,Tretinoin, which is a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR), can induce granulocytic differentiation and apoptosis in acute promyelocytic leukemia (APL) cells. Fenretinide chemical structure

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