Intracellular Signaling

Cell signaling (cell signalling in British English) is part of any communication process that governs basic activities of cells and coordinates all cell actions. The ability of cells to perceive and correctly respond to their microenvironment is the basis of development, tissue repair, and immunity, as well as normal tissue homeostasis. Errors in signaling interactions and cellular information processing are responsible for diseases such as cancer, autoimmunity, and diabetes. By understanding cell signaling, diseases may be treated more effectively and, theoretically, artificial tissues may be created.

Intracellular Signaling Products Targets

Products for Intracellular Signaling - Page 23

  1. Cat.No. Product Name Information/Activity
  2. BCC8091 U 73343 U-73343, an inhibitor of PLC (putative phospholipase C)-dependent processes, is an analog of U-73122 and can be used as a negative control. U 73343 chemical structure
  3. BCC7715 VU 0155069 VU0155069 (CAY10593), compound 69, is a selective phospholipase D1 (PLD1) inhibitor with an IC50 value of 46 nM in vitro. VU0155069 (CAY10593) strongly inhibits the invasive migration of several cancer cell lines in transwell assays. VU 0155069 chemical structure
  4. BCC7875 VU 0364739 hydrochloride 1244640-48-9 VU 0364739 hydrochloride chemical structure
  5. BCC7396 YM 26734 144337-18-8 YM 26734 chemical structure
  6. BCC7209 m-3M3FBS 200933-14-8 m-3M3FBS chemical structure
  7. BCC7210 o-3M3FBS 313981-55-4 o-3M3FBS chemical structure
  8. BCC3589 AM 114 856849-35-9 AM 114 chemical structure
  9. BCN1841 Lactacystin Lactacystin, an antibiotic Streptomyces spp. metabolite, is a potent and selective proteasome inhibitor with an IC50 of 4.8 μM for 20S proteasome. Lactacystin also inhibits the lysosomal enzyme cathepsin A. Lactacystin inhibits cell growth and induces neurite outgrowth. Lactacystin chemical structure
  10. BCC7848 AC 261066 AC-261066 is a potent, orally available and isoform-selective retinoic acid beta2 (RARbeta2) receptor agonist, with a pEC50 of 8.0. AC 261066 chemical structure
  11. BCC7359 AC 55649 AC-55649 is a potent, highly isoform-selective agonist of human RARβ2 receptor, with a pEC50 of 6.9. AC 55649 chemical structure

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