Intracellular Signaling

Cell signaling (cell signalling in British English) is part of any communication process that governs basic activities of cells and coordinates all cell actions. The ability of cells to perceive and correctly respond to their microenvironment is the basis of development, tissue repair, and immunity, as well as normal tissue homeostasis. Errors in signaling interactions and cellular information processing are responsible for diseases such as cancer, autoimmunity, and diabetes. By understanding cell signaling, diseases may be treated more effectively and, theoretically, artificial tissues may be created.

Intracellular Signaling Products Targets

Products for Intracellular Signaling - Page 21

  1. Cat.No. Product Name Information/Activity
  2. BCN2315 Pristimerin Pristimerin is a potent and reversible monoacylglycerol lipase (MGL) inhibitor with an IC50 of 93 nM. Pristimerin chemical structure
  3. BCC7949 PS 1145 dihydrochloride 1049743-58-9 PS 1145 dihydrochloride chemical structure
  4. BCC1124 PSI 158442-41-2 PSI chemical structure
  5. BCC6766 Pyrrolidinedithiocarbamate ammonium Pyrrolidinedithiocarbamate ammonium (Ammonium pyrrolidinedithiocarbamate) is a selective NF-κB inhibitor. Pyrrolidinedithiocarbamate ammonium chemical structure
  6. BCC7175 Ro 106-9920 62645-28-7 Ro 106-9920 chemical structure
  7. BCC4554 SC-514 SC-514 is a selective IKK-2 inhibitor (IC50=11.2 μM), which does not inhibit other IKK isoforms or other serine-threonine and tyrosine kinases. SC-514 chemical structure
  8. BCC2545 Sulfasalazine Sulfasalazine is a drug for the treatment of rheumatoid arthritis and ulcerative colitis. Sulfasalazine is reported to suppress NF-κB activity. Sulfasalazine chemical structure
  9. BCN5763 Tanshinone IIA Tanshinone IIA (Tan IIA) is one of the main fat-soluble compositions in the root of red-rooted salvia. Tanshinone IIA may suppress angiogenesis by targeting the protein kinase domains of VEGF/VEGFR2. Tanshinone IIA chemical structure
  10. BCC2473 TPCA-1 TPCA-1 is a potent and selective inhibitor of IKK-2 with IC50 of 17.9 nM. TPCA-1 is an effective inhibitor of STAT3 phosphorylation, DNA binding, and transactivation. TPCA-1 chemical structure
  11. BCC7495 Withaferin A Withaferin A is a steroidal lactone isolated from Withania somnifera, inhibits NF-kB activation and targets vimentin, with potent antiinflammatory and anticancer activities. Withaferin A chemical structure

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