Viscidulin IIICAS# 92519-91-0 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 92519-91-0 | SDF | Download SDF |
| PubChem ID | 5271991 | Appearance | Yellow powder |
| Formula | C17H14O8 | M.Wt | 346.3 |
| Type of Compound | Flavonoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 2-(3,6-dihydroxy-2-methoxyphenyl)-5,7-dihydroxy-8-methoxychromen-4-one | ||
| SMILES | COC1=C(C=CC(=C1C2=CC(=O)C3=C(O2)C(=C(C=C3O)O)OC)O)O | ||
| Standard InChIKey | CPFJPTACQDZPLS-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C17H14O8/c1-23-15-8(19)4-3-7(18)14(15)12-6-10(21)13-9(20)5-11(22)16(24-2)17(13)25-12/h3-6,18-20,22H,1-2H3 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | Viscidulin III (17.4 microM), wogonin (17.4 microM) and luteolin (18.4 microM) were more effective than baicalein (23.0 microM) which reportedly inhibits the proliferation of some cancer cell lines. |
| In vitro | Flavonoids from Scutellaria baicalensis and their bioactivities.[Pubmed: 19829679]Beijing Da Xue Xue Bao. 2009 Oct 18;41(5):578-84.To study the flavonoids of Scutellaria baicalensis and their bioactivities.
Cytotoxic activities of flavonoids from two Scutellaria plants in Chinese medicine.[Pubmed: 15036470]J Ethnopharmacol. 2004 Mar;91(1):65-8.The effects of 17 flavonoids, isolated from two flavonoid-rich Scutellaria species (Scutellaria baicalensis Georgi and Scutellaria rivularis Wall) used in traditional Chinese medicine, on HL-60 cells were assessed by WST-8.
|
| Structure Identification | Planta Med. 1997 Dec;63(6):536-9.Studies on the constituents of roots of Scutellaria planipes.[Pubmed: 17252377]From the roots of Scutellaria planipes (L.), three new flavonoids, 5,7,3',6'-tetrahydroxy-6,8,2'-trimethoxyflavone, (2 R,3 R)-3,5,7,2',5'-pentahydroxyflavanone and 7,2'-dihydroxy-5-methoxyflavone were isolated, together with ten known flavonoids, skullcapflavone I, wogonin, baicalein, norwogonin, Viscidulin III, 5,7,2',6'-tetrahydroxy-flavone, 3,5,7,2',6'-pentahydroxyflavone, wogonin 7- O-beta- D-glucuronide, baicalin, baicalein 7- O-beta- D-glucopyranoside, and three phenethyl alcohol glycosides, acteoside, martynoside, and jionoside D. The structures were elucidated by spectroscopic methods. |
Viscidulin III Dilution Calculator
Viscidulin III Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.8877 mL | 14.4383 mL | 28.8767 mL | 57.7534 mL | 72.1917 mL |
| 5 mM | 0.5775 mL | 2.8877 mL | 5.7753 mL | 11.5507 mL | 14.4383 mL |
| 10 mM | 0.2888 mL | 1.4438 mL | 2.8877 mL | 5.7753 mL | 7.2192 mL |
| 50 mM | 0.0578 mL | 0.2888 mL | 0.5775 mL | 1.1551 mL | 1.4438 mL |
| 100 mM | 0.0289 mL | 0.1444 mL | 0.2888 mL | 0.5775 mL | 0.7219 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
- 21-Deoxyneridienone B
Catalog No.:BCN4463
CAS No.:924910-83-8
- Rupesin E
Catalog No.:BCN7009
CAS No.:924901-58-6
- 4,5-Epoxyartemisinic acid
Catalog No.:BCN4462
CAS No.:92466-31-4
- AZD-5597
Catalog No.:BCC6453
CAS No.:924641-59-8
- T 5601640
Catalog No.:BCC5617
CAS No.:924473-59-6
- AdipoRon
Catalog No.:BCC4756
CAS No.:924416-43-3
- HBX 41108
Catalog No.:BCC6137
CAS No.:924296-39-9
- DUBs-IN-2
Catalog No.:BCC5257
CAS No.:924296-19-5
- DUBs-IN-1
Catalog No.:BCC5256
CAS No.:924296-18-4
- DUBs-IN-3
Catalog No.:BCC5258
CAS No.:924296-17-3
- 3-Acetoxy-4-cadinen-8-one
Catalog No.:BCN4461
CAS No.:923950-05-4
- Simeprevir
Catalog No.:BCC1949
CAS No.:923604-59-5
- Viscidulin II
Catalog No.:BCN3187
CAS No.:92519-93-2
- Viscidulin I
Catalog No.:BCN4465
CAS No.:92519-95-4
- Jingzhaotoxin III
Catalog No.:BCC6327
CAS No.:925463-91-8
- 10-DEBC hydrochloride
Catalog No.:BCC7409
CAS No.:925681-41-0
- KU-60019
Catalog No.:BCC3699
CAS No.:925701-49-1
- Acitretin sodium
Catalog No.:BCC4299
CAS No.:925701-88-8
- 3-Isomangostin hydrate formate
Catalog No.:BCN4466
CAS No.:925705-36-8
- TG100713
Catalog No.:BCC4985
CAS No.:925705-73-3
- Secaubryenol
Catalog No.:BCN4467
CAS No.:925932-08-7
- Secaubrytriol
Catalog No.:BCN4468
CAS No.:925932-10-1
- Dayecrystal A
Catalog No.:BCN4859
CAS No.:926010-24-4
- AMTB hydrochloride
Catalog No.:BCC7834
CAS No.:926023-82-7
Cytotoxic activities of flavonoids from two Scutellaria plants in Chinese medicine.[Pubmed:15036470]
J Ethnopharmacol. 2004 Mar;91(1):65-8.
The effects of 17 flavonoids, isolated from two flavonoid-rich Scutellaria species (Scutellaria baicalensis Georgi and Scutellaria rivularis Wall) used in traditional Chinese medicine, on HL-60 cells were assessed by WST-8. Ten of the flavonoids inhibited the proliferation of HL-60, as shown by IC50 values used as indexes of the inhibition. 2',3',5,7-tetrahydroxy flavone (IC50=9.5 microM), apigenin (15.0 microM), Viscidulin III (17.4 microM), wogonin (17.4 microM) and luteolin (18.4 microM) were more effective than baicalein (23.0 microM) which reportedly inhibits the proliferation of some cancer cell lines. Others were less effective, and oroxylin A stimulated the proliferation. Scutellaria rivularis, used for the treatment of tumors in the clinic, contained flavonoids that were more inhibitive than those in Scutellaria baicalensis. These results are demonstrative of some reasons for the use of Scutellaria rivularis as a crude antitumor drug.
Studies on the constituents of roots of Scutellaria planipes.[Pubmed:17252377]
Planta Med. 1997 Dec;63(6):536-9.
From the roots of Scutellaria planipes (L.), three new flavonoids, 5,7,3',6'-tetrahydroxy-6,8,2'-trimethoxyflavone, (2 R,3 R)-3,5,7,2',5'-pentahydroxyflavanone and 7,2'-dihydroxy-5-methoxyflavone were isolated, together with ten known flavonoids, skullcapflavone I, wogonin, baicalein, norwogonin, Viscidulin III, 5,7,2',6'-tetrahydroxy-flavone, 3,5,7,2',6'-pentahydroxyflavone, wogonin 7- O-beta- D-glucuronide, baicalin, baicalein 7- O-beta- D-glucopyranoside, and three phenethyl alcohol glycosides, acteoside, martynoside, and jionoside D. The structures were elucidated by spectroscopic methods.
[Flavonoids from Scutellaria baicalensis and their bioactivities].[Pubmed:19829679]
Beijing Da Xue Xue Bao Yi Xue Ban. 2009 Oct 18;41(5):578-84.
OBJECTIVE: To study the flavonoids of Scutellaria baicalensis and their bioactivities. METHODS: Chromatographic methods were used to separate compounds, spectral methods were used to determine the structures and bioactivities of the flavonoids were screened in several models in vitro. RESULTS: Nine compounds were isolated and identified as baicalein (1), wogonin (2), oroxylin A (3), 5, 7, 2', 6'-tetrahydroxyflavone (4), Viscidulin III (5), baicalin (6), wogonoside (7), oroxylin A-7-O-beta-D-glucuronide (8) and chrysin-6-C-alpha-L-arabinopyranosyl-8-C-beta-D-glucopyranoside (9). CONCLUSION: Baicalein had good anti-bacteria activity, and some compounds showed inhibiting activity against IL-1beta converting enzyme. The 13C NMR data of compounds 9 were assigned correctly by 2D nuclear magnetic resonance (NMR).
