4'-HydroxywogoninCAS# 57096-02-3 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 57096-02-3 | SDF | Download SDF |
| PubChem ID | 5322078 | Appearance | Yellow powder |
| Formula | C16H12O6 | M.Wt | 300.3 |
| Type of Compound | Flavonoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 5,7-dihydroxy-2-(4-hydroxyphenyl)-8-methoxychromen-4-one | ||
| SMILES | COC1=C(C=C(C2=C1OC(=CC2=O)C3=CC=C(C=C3)O)O)O | ||
| Standard InChIKey | OEZZJTAJYYSQKM-UHFFFAOYSA-N | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | 4'-Hydroxywogonin has positive effect on inhabiting those human tumor lines in vitro, with IC50 value is 8.3-38.4ug/mL . |
| Targets | NO |
| In vitro | Chromatographic fingerprint and quantitative analysis of seven bioactive compounds of Scutellaria barbata.[Pubmed: 20862635]Planta Med. 2011 Mar;77(4):388-93.Scutellaria barbata D. Don is widely used as a folk antitumor and anti-inflammatory agent in Asia. However, a simple and global quality control method for S. barbata was lacking. In this study, six phenolic compounds, including P-coumaric acid, scutellarin, apigenin 5-O-β-glucopyranoside, luteolin, apigenin and 4'-Hydroxywogonin were obtained from S. barbata by phytochemical investigations. |
| Structure Identification | Nat Prod Res. 2013 Oct;27(20):1930-2.Flavonoids of Dikamali: A phytochemical reinvestigation.[Pubmed: 23537094]
Zhong Yao Cai. 2006 Jul;29(7):677-9.Studies on chemical constituents of flavonoid from Verbena officinals.[Pubmed: 17059005]Five compounds have been isolated from Verbena offcinals L. On the basis of spectral analysis and physicochemical properties, the compounds were identified as luteolin (1), kaempferol (2), quercetin (3), apigenin (4) and 4'-Hydroxywogonin (5). 1, 2 and 3 were obtained from the genus for the first time. |
4'-Hydroxywogonin Dilution Calculator
4'-Hydroxywogonin Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 3.33 mL | 16.65 mL | 33.3 mL | 66.6001 mL | 83.2501 mL |
| 5 mM | 0.666 mL | 3.33 mL | 6.66 mL | 13.32 mL | 16.65 mL |
| 10 mM | 0.333 mL | 1.665 mL | 3.33 mL | 6.66 mL | 8.325 mL |
| 50 mM | 0.0666 mL | 0.333 mL | 0.666 mL | 1.332 mL | 1.665 mL |
| 100 mM | 0.0333 mL | 0.1665 mL | 0.333 mL | 0.666 mL | 0.8325 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Chromatographic fingerprint and quantitative analysis of seven bioactive compounds of Scutellaria barbata.[Pubmed:20862635]
Planta Med. 2011 Mar;77(4):388-93.
Scutellaria barbata D. Don is widely used as a folk antitumor and anti-inflammatory agent in Asia. However, a simple and global quality control method for S. barbata was lacking. In this study, six phenolic compounds, including P-coumaric acid, scutellarin, apigenin 5-O-beta-glucopyranoside, luteolin, apigenin and 4'-hydroxywogonin were obtained from S. barbata by phytochemical investigations. The six compounds plus baicalein show cytotoxcities to the nine human cancer cells, K562, MGC-803, HL60, SH-SY5Y, SW1116, SMMC-7221, SW480, HepG2 and KB. Subsequently, a high-performance liquid chromatography with photodiode array detector (HPLC-DAD) was developed for both fingerprint analysis of S. barbata and quantitative determination of the seven anticancer active compounds in S. barbata. The chromatographic separation was accomplished on an Ultimate XB-C18 column (4.6 x 250 mm, 5 microm) in 65 min. For fingerprinting, 26 common peaks were found and selected as characteristic peaks to assess the consistency of S. barbata samples. For quantitative analysis, the seven bioactive compounds showed good regression relationship ( R(2) > 0.999) within test ranges and the recovery of the method was in the range of 90-105 %. In brief, the present study provides the fingerprint analysis and quantitative methods for global and systematical quality control of S. barbata for its anticancer usage.
[Studies on the chemical constitutents in herb of Verbena officinalis].[Pubmed:15724402]
Zhongguo Zhong Yao Za Zhi. 2005 Feb;30(4):268-9.
OBJECTIVE: To isolate and identify the chemical constituents from Verbena officinalis. METHOD: The compounds were isolated by means of chromatography and the structures were determined on the basis of physical and spectral analysis. RESULT: Four compounds were isolated and identified as apigenin (I), 4'-hydroxywogonin (II), verbenalin (III) and hastatoside (IV). CONCLUSION: Compounds I and II were obtained from the genus for the first time.
Flavonoids of Dikamali: A phytochemical reinvestigation.[Pubmed:23537094]
Nat Prod Res. 2013 Oct;27(20):1930-2.
Eleven known flavonoids (1-11) were isolated from Dikamali, the gum resin of Gardenia lucida. Three of them, desmethylnobiletin, pectolinarigenin and xanthomicrol, are a new report from this source. Nuclear magnetic resonance (NMR) data are being given for all the isolates. For two of them, viz., 3',4'-dimethoxywogonin and 4'-hydroxywogonin, such data have not been reported in literature. Furthermore, correct NMR data are being provided for gardenin C as the data reported in literature were found to be incorrect.
[Studies on chemical constituents of flavonoid from Verbena officinals].[Pubmed:17059005]
Zhong Yao Cai. 2006 Jul;29(7):677-9.
Five compounds have been isolated from Verbena offcinals L. On the basis of spectral analysis and physicochemical properties, the compounds were identified as luteolin (1), kaempferol (2), quercetin (3), apigenin (4) and 4'-hydroxywogonin (5). 1, 2 and 3 were obtained from the genus for the first time.
