21-Deoxyneridienone BCAS# 924910-83-8 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 924910-83-8 | SDF | Download SDF |
| PubChem ID | 16104854 | Appearance | Powder |
| Formula | C21H28O3 | M.Wt | 328.5 |
| Type of Compound | Steroids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | (8R,9S,10R,13S,14S,17S)-17-[(1R)-1-hydroxyethyl]-10,13-dimethyl-2,8,9,11,14,15,16,17-octahydro-1H-cyclopenta[a]phenanthrene-3,12-dione | ||
| SMILES | CC(C1CCC2C1(C(=O)CC3C2C=CC4=CC(=O)CCC34C)C)O | ||
| Standard InChIKey | AXIMAQIOARWDAI-LYJJHTRHSA-N | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The herbs of Marsdenia tenacissima
21-Deoxyneridienone B Dilution Calculator
21-Deoxyneridienone B Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 3.0441 mL | 15.2207 mL | 30.4414 mL | 60.8828 mL | 76.1035 mL |
| 5 mM | 0.6088 mL | 3.0441 mL | 6.0883 mL | 12.1766 mL | 15.2207 mL |
| 10 mM | 0.3044 mL | 1.5221 mL | 3.0441 mL | 6.0883 mL | 7.6104 mL |
| 50 mM | 0.0609 mL | 0.3044 mL | 0.6088 mL | 1.2177 mL | 1.5221 mL |
| 100 mM | 0.0304 mL | 0.1522 mL | 0.3044 mL | 0.6088 mL | 0.761 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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A novel HLA-B allele, HLA-B*35:348, was identified by sequencing-based typing.[Pubmed:29024525]
HLA. 2018 Jan;91(1):68-69.
HLA-B*35:348 has 1 nucleotide substitution, c.817G > C (GTG-->CTG at codon 248) compared with B*35:01:01:01.
Unprecedented Sensitivity in a Probe for Monitoring Cathepsin B: Chemiluminescence Microscopy Cell-Imaging of a Natively Expressed Enzyme.[Pubmed:29024539]
Angew Chem Int Ed Engl. 2017 Dec 4;56(49):15633-15638.
Until recently, chemiluminescence cell images could only be obtained using luciferase-activated probes. Moreover, chemiluminescence microscopy cell-imaging has not been demonstrated for natively expressed enzymes like cathepsin B. Herein, we describe the design, synthesis, and evaluation of the first chemiluminescence probe for the detection and imaging of cathepsin B. The probe activation mechanism relies on the release of a dioxetane intermediate, which undergoes chemiexcitation to emit green light with high efficiency under physiological conditions. Using the probe, we obtained clear images of cancerous leukemia and colon cells. This is the first demonstration of chemiluminescence cell images obtained by a probe for a natively expressed endogenous enzyme. We anticipate that the concept presented in this study will be broadly used to develop analogous probes for other important proteases relevant to biomolecular processes.
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