Leucoside

CAS# 27661-51-4

Leucoside

Catalog No. BCN5167----Order now to get a substantial discount!

Product Name & Size Price Stock
Leucoside:10mg $268.00 In stock
Leucoside:20mg $456.00 In stock
Leucoside:50mg $1072.00 In stock
Leucoside:100mg $1876.00 In stock

Quality Control of Leucoside

Number of papers citing our products

Chemical structure

Leucoside

3D structure

Chemical Properties of Leucoside

Cas No. 27661-51-4 SDF Download SDF
PubChem ID 44566720 Appearance Yellowish powder
Formula C26H28O15 M.Wt 580.5
Type of Compound Flavonoids Storage Desiccate at -20°C
Synonyms Leucoside
Solubility Soluble in methanol and water
Chemical Name 3-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxyoxan-2-yl]oxy-5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one
SMILES C1C(C(C(C(O1)OC2C(C(C(OC2OC3=C(OC4=CC(=CC(=C4C3=O)O)O)C5=CC=C(C=C5)O)CO)O)O)O)O)O
Standard InChIKey RXAXTTGJEMODPY-CJNLAGEVSA-N
Standard InChI InChI=1S/C26H28O15/c27-7-15-18(33)20(35)24(41-25-21(36)17(32)13(31)8-37-25)26(39-15)40-23-19(34)16-12(30)5-11(29)6-14(16)38-22(23)9-1-3-10(28)4-2-9/h1-6,13,15,17-18,20-21,24-33,35-36H,7-8H2/t13-,15-,17+,18-,20+,21-,24-,25+,26+/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Leucoside

1 Helleborus sp. 2 Ilex sp. 3 Rhodiola sp.

Biological Activity of Leucoside

DescriptionPure leucoside can be prepared by enzymatic partial hydrolysis of tea seed extract .

Protocol of Leucoside

Structure Identification
J Sci Food Agric. 2013 Jan;93(2):362-7.

Novel synthesis of leucoside by enzymatic hydrolysis of tea seed extract.[Pubmed: 22777867]

The application of tea seed extract (TSE) has been widely investigated owing to its biological activities. In this paper, two flavonol triglycosides found in TSE, camelliaside A (CamA) and camelliaside B (CamB), were subjected to hydrolysis in the presence of three commercial enzyme complexes of the Pectinex® series, 5XL, XXL and Ultra SP-L (Ultra).
METHODS AND RESULTS:
XXL and 5XL induced stepwise deglycosylation of CamA and CamB to yield kaempferol diglycoside (nicotiflorin), kaempferol monoglycoside (astragalin) and kaempferol, while Ultra produced an additional new compound (1) that had not been observed in earlier studies. Upon hydrolysis of isolated CamA and CamB, compound (1) was obtained only from CamB. Both the molecular ion peak in liquid chromatography/mass spectrometry and the ¹H and ¹³C nuclear magnetic resonance spectra of (1) isolated by Ultra-induced hydrolysis of TSE indicated that (1) was kaempferol 3-O-β-xylopyranosyl (1 → 2)-β-glucopyranoside (Leucoside), formed by selective hydrolysis of the rhamnosyl moiety of CamB.
CONCLUSIONS:
Pure Leucoside can be prepared by enzymatic partial hydrolysis of TSE. This is the first study to address the synthesis of pure Leucoside from a natural source.

Leucoside Dilution Calculator

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Leucoside Molarity Calculator

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Preparing Stock Solutions of Leucoside

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.7227 mL 8.6133 mL 17.2265 mL 34.4531 mL 43.0663 mL
5 mM 0.3445 mL 1.7227 mL 3.4453 mL 6.8906 mL 8.6133 mL
10 mM 0.1723 mL 0.8613 mL 1.7227 mL 3.4453 mL 4.3066 mL
50 mM 0.0345 mL 0.1723 mL 0.3445 mL 0.6891 mL 0.8613 mL
100 mM 0.0172 mL 0.0861 mL 0.1723 mL 0.3445 mL 0.4307 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Leucoside

Novel synthesis of leucoside by enzymatic hydrolysis of tea seed extract.[Pubmed:22777867]

J Sci Food Agric. 2013 Jan;93(2):362-7.

BACKGROUND: The application of tea seed extract (TSE) has been widely investigated owing to its biological activities. In this paper, two flavonol triglycosides found in TSE, camelliaside A (CamA) and camelliaside B (CamB), were subjected to hydrolysis in the presence of three commercial enzyme complexes of the Pectinex(R) series, 5XL, XXL and Ultra SP-L (Ultra). RESULTS: XXL and 5XL induced stepwise deglycosylation of CamA and CamB to yield kaempferol diglycoside (nicotiflorin), kaempferol monoglycoside (astragalin) and kaempferol, while Ultra produced an additional new compound (1) that had not been observed in earlier studies. Upon hydrolysis of isolated CamA and CamB, compound (1) was obtained only from CamB. Both the molecular ion peak in liquid chromatography/mass spectrometry and the (1)H and (1)(3)C nuclear magnetic resonance spectra of (1) isolated by Ultra-induced hydrolysis of TSE indicated that (1) was kaempferol 3-O-beta-xylopyranosyl (1 --> 2)-beta-glucopyranoside (Leucoside), formed by selective hydrolysis of the rhamnosyl moiety of CamB. CONCLUSION: Pure Leucoside can be prepared by enzymatic partial hydrolysis of TSE. This is the first study to address the synthesis of pure Leucoside from a natural source.

Description

Leucoside is a natural compound isolated from tea seed extract.

Keywords:

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