8-HydroxybergaptenCAS# 1603-47-0 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 1603-47-0 | SDF | Download SDF |
| PubChem ID | 3083726 | Appearance | Cryst. |
| Formula | C12H8O5 | M.Wt | 232.19 |
| Type of Compound | Coumarins | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 9-hydroxy-4-methoxyfuro[3,2-g]chromen-7-one | ||
| SMILES | COC1=C2C=COC2=C(C3=C1C=CC(=O)O3)O | ||
| Standard InChIKey | MVJHUMZXIJPVHV-UHFFFAOYSA-N | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | 8-Hydroxybergapten may have anti-wrinkle activity. |
| In vitro | Effect of Angelica. against Skin Photo-aging.[Reference: WebLink]Journal of the Society of Cosmetic Scientists of Korea, 2005,31(3):227-35.Skin aging is not a disease nor an abnormal phenomenon but a collection of degenerative changes with age, characterized by skin dryness, wrinkle formation, and loss of skin elasticity. |
8-Hydroxybergapten Dilution Calculator
8-Hydroxybergapten Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 4.3068 mL | 21.5341 mL | 43.0682 mL | 86.1364 mL | 107.6704 mL |
| 5 mM | 0.8614 mL | 4.3068 mL | 8.6136 mL | 17.2273 mL | 21.5341 mL |
| 10 mM | 0.4307 mL | 2.1534 mL | 4.3068 mL | 8.6136 mL | 10.767 mL |
| 50 mM | 0.0861 mL | 0.4307 mL | 0.8614 mL | 1.7227 mL | 2.1534 mL |
| 100 mM | 0.0431 mL | 0.2153 mL | 0.4307 mL | 0.8614 mL | 1.0767 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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The biosynthesis of isopimpinellin.[Pubmed:890566]
Can J Biochem. 1977 Jul;55(7):686-92.
Bergapten and xanthotoxin, labelling in the methyl group wich carbon-14 or tritiated at three skeletal carbons, were administered to leaves of Heracleum lanatum and to cell cultures of Ruta graveolens. In all experiments xanthotoxin was the more efficient precursor of isopimpinellin, although bergapten was always incorporated to a measurable extent. Double-labelling experiments showed that both precursors, especially bergapten, underwent considerable demethylation (and presumably remethylation) before conversion to isopimpinellin. 5-Hydroxyxanthotoxin and 8-Hydroxybergapten were both O-methylated by cell-free extracts of Ruta cells to isopimpinellin, in reactions mediated by discrete O-methyltransferases. 8-Hydroxy[Me-14C]bergapten was converted with a high degree of incorporation to isopimpinellin by Ruta cells in vivo, and it is suggested that the preference for the pathway via xanthotoxin may be due to more rapid hydroxylation of this substrate.
