8-DebenzoylpaeoniflorinCAS# 23532-11-8 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 23532-11-8 | SDF | Download SDF |
| PubChem ID | 71452333 | Appearance | Powder |
| Formula | C16H24O10 | M.Wt | 376.4 |
| Type of Compound | N/A | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| SMILES | CC12CC3(C4CC1(C4(C(O2)O3)CO)OC5C(C(C(C(O5)CO)O)O)O)O | ||
| Standard InChIKey | LTXNSYGCFNCQRW-DKCIEBLWSA-N | ||
| Standard InChI | InChI=1S/C16H24O10/c1-13-4-15(22)7-2-16(13,14(7,5-18)12(25-13)26-15)24-11-10(21)9(20)8(19)6(3-17)23-11/h6-12,17-22H,2-5H2,1H3/t6-,7-,8-,9+,10-,11+,12-,13+,14+,15-,16+/m1/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
8-Debenzoylpaeoniflorin Dilution Calculator
8-Debenzoylpaeoniflorin Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.6567 mL | 13.2837 mL | 26.5675 mL | 53.135 mL | 66.4187 mL |
| 5 mM | 0.5313 mL | 2.6567 mL | 5.3135 mL | 10.627 mL | 13.2837 mL |
| 10 mM | 0.2657 mL | 1.3284 mL | 2.6567 mL | 5.3135 mL | 6.6419 mL |
| 50 mM | 0.0531 mL | 0.2657 mL | 0.5313 mL | 1.0627 mL | 1.3284 mL |
| 100 mM | 0.0266 mL | 0.1328 mL | 0.2657 mL | 0.5313 mL | 0.6642 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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[Chemical constituents from seeds of Paeonia suffruticosa].[Pubmed:20822014]
Zhongguo Zhong Yao Za Zhi. 2010 Jun;35(11):1428-31.
OBJECTIVE: To study the chemical constituents from seeds of Paeonia sufruticosa. METHOD: Various chromatographic techniques were used to isolate and purify the constituents, their physico-chemical properties and spectral data were employed to elucidate their structures. RESULT: Thirteen compounds were isolated and identified as: paeoniflorin (1), oxypaeoniflorin (2), 6'-O-beta-D-glucopyranosylalbiflorin (3), 8-Debenzoylpaeoniflorin (4), 8-debenzoylpaeonidanin (5), 1-O-beta-D-glucopyranosylpaeonisuf-frone (6), 1-O-beta-D-ethyl-mannopyranoside (7), sucrose (8), luteolin (9), apigenin (10), benzoic acid (11) and 1-0-beta-D-(4-hydroxybenzoyl) glucose (12). CONCLUSION: compounds 2, 4-6 were isolated from this plant for the first time, compounds 7 and 12 were isolated from the family of Paeoniaceae for the first time.
Pangelin, an antimycobacterial coumarin from Ducrosia anethifolia.[Pubmed:14648403]
Planta Med. 2003 Oct;69(10):956-9.
The aerial parts of Ducrosia anethifolia afforded the monoterpene glucoside 8-Debenzoylpaeoniflorin ( 1) and the prenylated furanocoumarin pangelin [5-[2"( R)-hydroxy-3"-methyl-3"-butenyloxy]furocoumarin] ( 2). Their structures were determined by extensive 1- and 2-dimensional NMR studies. Compound 2 demonstrated activity against a panel of fast growing mycobacteria, namely Mycobacterium fortuitum, M. aurum, M. phlei and M. smegmatis and minimum inhibitory concentration (MIC) values ranged from 64 - 128 microg/mL. Whilst compounds 1 and 2 have previously been reported as an antihyperglycaemic component from Paeonia lactiflora, and as a constituent of Angelica pancici, respectively, this is the first report of the full (1)H- and (13)C-NMR data for these natural products.
Antihyperglycemic effects of paeoniflorin and 8-debenzoylpaeoniflorin, glucosides from the root of Paeonia lactiflora.[Pubmed:9270377]
Planta Med. 1997 Aug;63(4):323-5.
Paeoniflorin and 8-Debenzoylpaeoniflorin were isolated from the dried root of Paeonia lactiflora Pall. (Ranunculaceae). They produced a significant blood sugar lowering effect in streptozotocin-treated rats and had a maximum effect at 25 min after treatment. This hypoglycemic action was also observed in normoglycemic rats only at 1 mg/kg. The antihyperglycemic activity of 8-Debenzoylpaeoniflorin seems lower than that of paeoniflorin. Plasma insulin was not changed in paeoniflorin-treated normoglycemic rats indicating an insulin-independent action. Also, this glucoside reduced the elevation of blood sugar in glucose challenged rats. Increase of glucose utilization by paeoniflorin can thus be considered. There are no previous data showing the hypoglycemic activity of paeoniflorin and/or 8-Debenzoylpaeoniflorin in rats.
