BCN2235EstriolEstriol is an antagonist of the G-protein coupled estrogen receptor in estrogen receptor-negative breast cancer cells.(CAS NO.:50-27-1)
BCN2194beta-EstradiolEstradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females.(CAS NO.:50-28-2)
BCN2839PennogeninBotanical source: The rhizomes of Paris yunnanensis Franch.(CAS NO.:507-89-1)
BCN2401Polyphyllin DPolyphyllin I is a bioactive constituent extracted from Paris polyphylla, has strong anti-tumor activity. Polyphyllin I is an activator of the JNK signaling pathway and is an inhibitor of PDK1/Akt/mTOR signaling. Polyphyllin I induces autophagy, G2/M phase arrest and apoptosis.(CAS NO.:50773-41-6)
BCN2833Polyphyllin BFormosanin C is a diosgenin saponin isolated from Paris formosana Hayata and an immunomodulator with antitumor activity. Formosanin C induces apoptosis.(CAS NO.:50773-42-7)
BCN8238HellebrigenolBotanical source: The glandular body of Bufo bufo gargarizans Cantor.(CAS NO.:508-79-2)
BCN3886GitogeninGitogenin is a natural steroid isolated from the whole plant of Tribulus longipetalus. Gitogenin is a selective inhibitor of UDP-glucuronosyltransferase 1A4 (UGT1A4) and enzyme α-glucosidase with IC50 values of 0.69 μM (use trifluoperazine as a substrate) and 37.2 μM, respectively, and does not inhibit the activities of major human cytochrome P450 isoforms.(CAS NO.:511-96-6)
BCC7495Withaferin AWithaferin A is a steroidal lactone isolated from Withania somnifera, inhibits NF-kB activation and targets vimentin, with potent antiinflammatory and anticancer activities.(CAS NO.:5119-48-2)
BCN6272DiosgeninDiosgenin, a steroidal saponin, can inhibit STAT3 signaling pathway. Diosgenin is an exogenous activator of Pdia3/ERp57.(CAS NO.:512-04-9)
BCN2656PeriplogeninPeriplogenin is a naturally occurring furanocoumarin found in Angelica dahurica roots，with potent anti-psoriatic effects. Periplogenin induces adipocyte differentiation.(CAS NO.:514-39-6)
BCN5640CerevisterolBotanical source: The fruit body of Ganoderma lucidum(CAS NO.:516-37-0)
BCN568820-HydroxyecdysoneCrustecdysone (20-Hydroxyecdysone) is a naturally occurring ecdysteroid hormone isolated from Cyanotis arachnoides C.B.Clarke which controls the ecdysis (moulting) and metamorphosis of arthropods, it inhibits caspase activity and induces autophagy via the 20E nuclear receptor complex, EcR-USP. Crustecdysone exhibits regulatory or protective roles in the cardiovascular system.(CAS NO.:5289-74-7)
BCN2201EstroneEstrone is an estrogenic hormone.(CAS NO.:53-16-7)
BCN2202DehydroepiandrosteroneDHEA (Prasterone) is one of the most abundant steroid hormones. DHEA (Prasterone) mediates its action via multiple signaling pathways involving specific membrane receptors and via transformation into androgen and estrogen derivatives (e.g., androgens, estrogens, 7α and 7β DHEA, and 7α and 7β epiandrosterone derivatives) acting through their specific receptors.(CAS NO.:53-43-0)
BCN2836DichotominBotanical source: The rhizomes of Paris yunnanensis Franch.(CAS NO.:53093-47-3)
BCN75724beta-Hydroxywithanolide EBotanical source: The aerial parts of Physalis peruviana.(CAS NO.:54334-04-2)
BCN6342Methyl protodioscinMethyl protodioscin(NSC-698790) is a furostanol bisglycoside with antitumor properties; shows to reduce proliferation, cause cell cycle arrest.(CAS NO.:54522-52-0)
BCN8177Methyl protogracillinMethyl protogracillin (NSC-698793), isolated from the roots of Dioscorea opposite Thunb, exhibits strong anti-cancer activity.(CAS NO.:54522-53-1)
BCC8352Protogracillin(P)Protogracillin is a steroidal saponin isolated from Dioscorea zingiberensis Wright (DZW). Steroidal saponins from DZW rhizomes have the potential to reduce the risk of cardiovascular diseases by anti-thrombotic action.(CAS NO.:54848-30-5)
BCN6274ProtodioscinProtodioscin, a major steroidal saponin in dioscoreae rhizome, has been shown to exhibit multiple biological actions, such as anti-hyperlipidemia, anti-cancer, sexual effects and cardiovascular properties.(CAS NO.:55056-80-9)
BCC8933DeltoninDeltonin, a steroidal saponin, isolated from Dioscorea zingiberensis Wright, with antitumor activity; Deltonin inhibits ERK1/2 and AKT activation.(CAS NO.:55659-75-1)
BCN5745Stigmasta-4,22-dien-3-oneBotanical source: The flower of Magnolia biondii(CAS NO.:55722-32-2)
BCN1053Polyphyllin VIPolyphyllin VI, an active saponin mainly isolated from traditional medicinal plant Paris polyphylla, possess anti-cancer activities. Polyphyllin VI induces G2/M cell cycle arrest and triggers apoptosis.(CAS NO.:55916-51-3)
