Products with Inhibitors bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN1067 | Ginsenoside Rg2 |
| Ginsenoside Rg2 has therapeutic potential for type 2 diabetic patients, it also may represent a potential neurorestorative treatment strategy for vascular dementia or other ischemic insults, has protective effects against H2O2-induced injury and apoptosis in H9c2 cells. Ginsenoside Rg2 suppresses the hepatic glucose production via AMPK-induced phosphorylation of GSK3β and induction of SHP gene expression, regulates the 5-HT3A receptors that are expressed in Xenopus oocytes, inhibits nicotinic acetylcholine receptor-mediated Na+ influx and channel activity. | |
| BCN1079 | 20(R)-Protopanaxatriol |
| 20(R)-Protopanaxatriol shows anti-hyperglycaemic, and anti-cancer activities.Protopanaxatriol has inhibitory effects on the enzyme catalytic activities of cyclooxygenases-1 and -2 (COX-1 and -2). | |
| BCN1104 | Epifriedelanol |
| Epifriedelanol has antitumor activity, it can reduce cellular senescence in human primary cells and may be used to develop dietary supplements or cosmetics that modulate tissue aging or aging-associated diseases. Epifriedelanol exhibits significant inhibition of NF-kappa B, it may be used to treat asthma. | |
| BCN1130 | trans-Hinokiresinol |
| 1. Hinokiresinol (trans-hinokiresinol) and nyasol (cis-hinokiresinol) possess appreciable estrogen receptor binding activity, they can stimulate the proliferation of estrogen- dependent T47D breast cancer cells, and their stimulatory effects could be blocked by an estrogen antagonist, indicating that they are estrogen agonists. 2. trans- and cis-Hinokiresinols have similar free radical scavenging and anti-inflammatory activities, they also have anti-ischemic effects, only trans-hinokiresinol can significantly decrease neuronal injury in cultured cortical neurons exposed to oxygen-glucose deprivation followed by re-oxygenation. 3. Hinokiresinol is a novel inhibitor of LTB4 binding to the human neutrophils. 4. Hinokiresinol has antiallergic effect, it inhibits IgE-induced mouse passive cutaneous anaphylaxis reaction. | |
| BCN1132 | Hardwickiic acid |
| 1. Hardwickiic acid , a clerodane diterpenoid from Copaiba oil has been reported to inhibit Hsp27. 2. Hardwickiic acid modulates hippocampal [(3)H]NA overflow evoked by a mild depolarizing stimulus by acting at presynaptic opioid receptor subtypes. 3. Hardwickiic acid shows antimicrobial activity, it can inhibit the growth of all the tested microbial species. 4. (-)-Hardwickiic acid has insecticidal activity. | |
