Pain and Inflammation Research

Although separate conditions, pain and inflammation are nearly always associated with each other. Pain is defined by the International Association for the Study of Pain (IASP) as 'an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage'. Inflammation is the tissue's immunologic response to injury, characterized by mobilization of white blood cells and antibodies, swelling, and fluid accumulation.

Pain and Inflammation Research Products Areas

Products for Pain and Inflammation Research - Page 33

Cat.No. Product Name Information/Activity
BCC2362 SID 26681509 SID 26681509 is a potent, reversible, competitive, and selective inhibitor of human cathepsin L with an IC50 of 56 nM. SID 26681509 inhibits in vitro propagation of malaria parasite Plasmodium falciparum and inhibits Leishmania major with IC50s of 15.4 μM and 12.5 μM, respectively. SID 26681509 shows no inhibitory activity against cathepsin G.
BCC8039 PMX 205 PMX 205 is a potent complement C5a receptor (C5aR; CD88) antagonist.
BCC6067 Compstatin control peptide 301544-78-5
BCC7886 BTZO 1 BTZO-1 binds to Macrophage migration inhibitory factor (MIF) with a Kd value of 68.6 nM, and its binding requires the N-terminal Pro1. BTZO-1 can activate antioxidant response element (ARE)-mediated gene expression and suppress oxidative stress-induced cardiomyocyte apoptosis in vitro.
BCC6816 Chicago Sky Blue 6B 2610-05-1
BCC6161 (±)-CPSI 1306 (±)-CPSI-1306 is an orally available antagonist of macrophage migration inhibitory factor (MIF).
BCC5914 ER 27319 maleate 1204480-26-1
BCC2096 Gabexate mesylate Gabexate mesylate is a Factor X inhibitor; serine protease inhibitor .
BCC5203 VGX-1027 VGX-1027(GIT27) is an isoxazole compound that exhibits various immunomodulatory properties; reduce the secretion of IL-1beta, TNF-alpha and IL-10 from purified murine macrophages.
BCC6365 iMDK 881970-80-5