Pain and Inflammation Research

Although separate conditions, pain and inflammation are nearly always associated with each other. Pain is defined by the International Association for the Study of Pain (IASP) as 'an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage'. Inflammation is the tissue's immunologic response to injury, characterized by mobilization of white blood cells and antibodies, swelling, and fluid accumulation.

Pain and Inflammation Research Products Areas

Products for Pain and Inflammation Research - Page 24

Cat.No. Product Name Information/Activity
BCC7561 L-651,582 Carboxyamidotriazole (L-651582) is a cytostatic inhibitor of nonvoltage-operated calcium channels and calcium channel-mediated signaling pathways. Carboxyamidotriazole shows anti-tumor, anti-inflammatory and antiangiogenic effects.
BCC5238 Lercanidipine hydrochloride Lercanidipine hydrochloride is a calcium channel blocker of the dihydropyridine class.
BCC4380 Loperamide HCl Loperamide (hydrochloride) (R-18553 (hydrochloride)) is an opioid receptor agonist. Loperamide hydrochloride is a selective and competitive
BCC1749 Mibefradil dihydrochloride Mibefradil dihydrochloride (Ro 40-5967 dihydrochloride) is a calcium channel blocker with moderate selectivity for T-type Ca2+ channels displaying IC50s of 2.7 μM and 18.6 μM for T-type and L-type currents, respectively.
BCC4808 Nifedipine Nifedipine (BAY-a-1040) is a potent calcium channel blocker and drug of choice for cardiac insufficiencies.
BCC6947 (S)-(+)-Niguldipine hydrochloride 113145-69-0
BCC3799 Nilvadipine Nilvadipine is a potent calcium channel antagonist, and the IC50 value is around 0.1 nM.
BCC3823 Nimodipine Nimodipine(Nimotop) is a dihydropyridine derivative and an analogue of the calcium channel blocker nifedipine, with antihypertensive activity.
BCC4381 Nitrendipine Nitrendipine is a calcium channel blocker with marked vasodilator action.
BCC1803 NNC 55-0396 NNC 55-0396, Mibefradil derivative, is a highly selective T-type calcium channel blocker; displays IC50 values of 6.8 and > 100 μM for inhibition of Cav3.1 T-type channels and HVA currents respectively in INS-1 cells.