Pain and Inflammation Research
Although separate conditions, pain and inflammation are nearly always associated with each other. Pain is defined by the International Association for the Study of Pain (IASP) as 'an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage'. Inflammation is the tissue's immunologic response to injury, characterized by mobilization of white blood cells and antibodies, swelling, and fluid accumulation.
Pain and Inflammation Research Products Areas
Products for Pain and Inflammation Research - Page 110
- Cat.No. Product Name Information/Activity
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BCC7291
Carcinine ditrifluoroacetate
56897-53-1
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BCC6781
Clobenpropit dihydrobromide
Clobenpropit dihydrobromide is a potent histamine H3R antagonist/inverse agonist with a pEC50 of 8.07 for histamine H3LR. Clobenpropit dihydrobromide acts as partial agonist at histamine H4 receptors (Ki 13 nM). Clobenpropit dihydrobromide also binds to serotonin 5-HT3 receptors (Ki 7.4 nM) and α2A/α2C adrenoceptors (Ki 17.4/7.8 nM). Clobenpropit dihydrobromide increases apoptosis.
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BCC7352
Conessine
546-06-5
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BCC7357
GT 2016
152241-24-2
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BCC7197
Impentamine dihydrobromide
149629-70-9
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BCC6793
Iodophenpropit dihydrobromide
Iodophenpropit dihydrobromide is a potent and selective histamine H3 receptor antagonist. The binding of [125I]Iodophenpropit is selective, saturable, readily reversible, and of high affinity (KD 0.32 nM).
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BCC7842
JNJ 10181457 dihydrochloride
544707-20-2
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BCC6101
JNJ 5207852 dihydrochloride
JNJ-5207852 is a selective and potent histamine H3 receptor (H3R) antagonist, with pKis of 8.9, 9.24 for rat and human H3R, respectively.
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BCC7245
ROS 234 dioxalate
184576-87-2
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BCC6734
Thioperamide
106243-16-7


