Sleep Research
Sleep is characterized by altered consciousness, it is split into two distinct stages- rapid eye movement (REM) and non-REM. The circadian clock controls the pattern of sleep and wakefulness. It is regulated by the light levels, temperature, metabolites, neurotransmitters, neuropeptides, and neurohormones, which cause a daily fluctuation in expression levels of many sleep-related genes.
Sleep Research Products Targets
- Adenosine A2A Receptor (11)
- GABAB Receptor (28)
- 5-HT2C Receptor (23)
- 5-HT2B Receptor (12)
- 5-HT2A Receptor (25)
- Melatonin Receptor (10)
- GABAA-ρ Receptor (8)
- GABAA Receptor (66)
- Retinoic Acid-related Orphan Receptor (4)
- Rev-Erb Receptor (2)
- DREADD Ligands (1)
- D3 Receptor (12)
- 5-HT3 Receptor (39)
- D2 Receptor (14)
- Histamine H3 Receptor (22)
- Adenosine A1 Receptor (12)
- OX2 Receptor (4)
- OX1 Receptor (5)
Products for Sleep Research - Page 22
- Cat.No. Product Name Information/Activity
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BCC5705
Picrotoxin
Picrotoxin (Cocculin) is a natural noncompetitive antagonist of GABAA receptor, binds to the interface pocket on the GABAR. Picrotoxin (Cocculin) causes overstimulation and induces convulsions.
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BCC7266
SCS
3232-36-8
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BCC6997
SR 95531 hydrobromide
Gabazine is a selective and competitive antagonist of GABAA receptor, with an IC50 of ~0.2 μM for GABA receptor.
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BCC7510
TB 21007
207306-50-1
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BCC7471
U 93631
U93631 is a GABAA receptor ligand of novel chemical structure with IC50 of 100 nM,and has been shown to induce a rapid, time-dependent decay of GABA-induced whole-cell Cl-currents in recombinant GABAA receptors.
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BCC5521
Emapunil
Emapunil(AC-5216;XBD-173) is a translocator protein [TSPO (18 kDa)] ligand.
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BCC7711
Bretazenil
84379-13-5
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BCC6635
β-CCB
84454-35-3
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BCC7162
CL 218872
66548-69-4
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BCC6671
Dihydroergotoxine mesylate
Dihydroergotoxine mesylate is a complex of closely related alkaloid salts; Binds with high affinity to the GABAA receptor Cl- channel, producing an allosteric interaction with the benzodiazepine site.
