Sleep Research
Sleep is characterized by altered consciousness, it is split into two distinct stages- rapid eye movement (REM) and non-REM. The circadian clock controls the pattern of sleep and wakefulness. It is regulated by the light levels, temperature, metabolites, neurotransmitters, neuropeptides, and neurohormones, which cause a daily fluctuation in expression levels of many sleep-related genes.
Sleep Research Products Targets
- Adenosine A2A Receptor (11)
- GABAB Receptor (28)
- 5-HT2C Receptor (23)
- 5-HT2B Receptor (12)
- 5-HT2A Receptor (25)
- Melatonin Receptor (10)
- GABAA-ρ Receptor (8)
- GABAA Receptor (66)
- Retinoic Acid-related Orphan Receptor (4)
- Rev-Erb Receptor (2)
- DREADD Ligands (1)
- D3 Receptor (12)
- 5-HT3 Receptor (39)
- D2 Receptor (14)
- Histamine H3 Receptor (22)
- Adenosine A1 Receptor (12)
- OX2 Receptor (4)
- OX1 Receptor (5)
Products for Sleep Research - Page 17
- Cat.No. Product Name Information/Activity
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BCC7440
Fananserin
Fananserin (RP 62203) is an orally bioavailable, potent and selective 5-hydroxytryptamine2 (5-HT2) receptor antagonist, with a Ki of 0.37 nM for the rat 5-HT2A receptor. Fananserin also is a selective dopamine D4 receptor antagonist, with a Ki of 2.93 nM for the human dopamine D4 receptor.
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BCC7877
MDL 100907
Volinanserin is a potent and selective antagonist of 5-HT2 receptor, with a Ki of 0.36 nM, and shows 300-fold selectivity for 5-HT2 receptor over 5-HT1c, alpha-1 and DA D2 receptors. Volinanserin has antipsychotic activity.
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BCC6822
MDL 11,939
107703-78-6
-
BCC7139
Mesulergine hydrochloride
72786-12-0
-
BCC7479
Nefazodone hydrochloride
Nefazodone hydrochloride is an antidepressant drug.
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BCC7467
PNU 96415E
170856-41-4
-
BCC7164
R-96544 hydrochloride
167144-80-1
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BCC5247
Sarpogrelate hydrochloride
Sarpogrelate hydrochloride (MCI-9042), a selective 5-HT2 antagonist, has been widely used as an anti-platelet agent for the treatment of PAD.
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BCC6882
Spiperone hydrochloride
2022-29-9
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BCC6915
BW 723C86 hydrochloride
5-HT<sub>2B</sub> agonist
