Schizophrenia Research

Schizophrenia is a chronic, debilitating mental disorder affecting 1-2% of the global population. Symptoms are split into two types; 'positive' symptoms, including delusions and hallucinations, and 'negative' symptoms, including anhedonia and lack of motivation. Studies suggest that genetics, early environment, neurobiology, psychological and social processes are important contributory factors; some recreational and prescription drugs appear to cause or worsen symptoms. Several neurobiological alterations in brain structure, physiology and neurochemistry have been documented, along with an ever-increasing list of susceptibility genes.

Schizophrenia Research Products Targets

Products for Schizophrenia Research - Page 40

  1. Cat.No. Product Name Information/Activity
  2. BCC7819 TCS 1205 355022-97-8 TCS 1205 chemical structure
  3. BCC6803 THIP hydrochloride Gaboxadol hydrochloride (Lu 02-030 hydrochloride; THIP hydrochloride) is a potent agonist of the GABAA receptor and an antagonist of GABAC receptors (IC50=25 μM). Gaboxadol hydrochloride displays a partial agonist efficacy on subunit α1β2γ2 with an ED50 value of 143 µM, a full agonist efficacy at α5 subunit (ED50=28-129 µM) and a superagonist efficacy at α4β3δ (ED50=6 µM). Gaboxadol hydrochloride is a non-opioid analgesic and has hypnotic activities. THIP hydrochloride chemical structure
  4. BCC6169 TP 003 628690-75-5 TP 003 chemical structure
  5. BCC6563 ZAPA sulfate 371962-01-5 ZAPA sulfate chemical structure
  6. BCC7387 (-)-Bicuculline methiodide 40709-69-1 (-)-Bicuculline methiodide chemical structure
  7. BCC6555 (-)-Bicuculline methobromide (-)-Bicuculline methobromide (l-Bicuculline methobromide) is a potent GABAA receptor antagonist. (-)-Bicuculline methobromide blocks afterhyperpolarizations (AHPs) mediated by Ca2+-activated K+ channels in various types of neurons. (-)-Bicuculline methobromide chemical structure
  8. BCN3763 (-)-Bicuculline methochloride (-)-Bicuculline methochloride (l-Bicuculline methochloride) is a potent GABAA receptor antagonist. (-)-Bicuculline methochloride blocks afterhyperpolarizations (AHPs) mediated by Ca2+-activated K+ channels in various types of neurons. (-)-Bicuculline methochloride chemical structure
  9. BCN1238 (+)-Bicuculline (+)-Bicuculline is a light-sensitive competitive antagonist of GABA-A receptor. (+)-Bicuculline chemical structure
  10. BCC3782 Furosemide Furosemide is a loop diuretic inhibitor of Na+/2Cl-/K+ (NKCC) cotransporter of which used in the treatment of congestive heart failure and edema. Furosemide chemical structure
  11. BCC6193 PHP 501 trifluoroacetate 1236105-75-1 PHP 501 trifluoroacetate chemical structure

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