Schizophrenia Research

Schizophrenia is a chronic, debilitating mental disorder affecting 1-2% of the global population. Symptoms are split into two types; 'positive' symptoms, including delusions and hallucinations, and 'negative' symptoms, including anhedonia and lack of motivation. Studies suggest that genetics, early environment, neurobiology, psychological and social processes are important contributory factors; some recreational and prescription drugs appear to cause or worsen symptoms. Several neurobiological alterations in brain structure, physiology and neurochemistry have been documented, along with an ever-increasing list of susceptibility genes.

Schizophrenia Research Products Targets

Products for Schizophrenia Research - Page 21

  1. Cat.No. Product Name Information/Activity
  2. BCN2170 Varenicline tartrate Varenicline Tartrate(CP 526555;Champix) is a nicotinic receptor partial agonist; it stimulates nicotine receptors more weakly than nicotine itself does. Varenicline tartrate chemical structure
  3. BCC7341 Dihydro-β-erythroidine hydrobromide Dihydro-β-erythroidine (DHβE) hydrobromide is a potent, orally active and competitive antagonist of neuronal nicotinic acetyicholine receptors (nAChRs). Dihydro-β-erythroidine hydrobromide shows selectivity for α4β4 and α4β2 nAChRs, with IC50s of 0.19 and 0.37 μM, respectively. Antidepressant-like activities. Dihydro-β-erythroidine hydrobromide chemical structure
  4. BCC7301 DMAB-anabaseine dihydrochloride 154149-38-9 DMAB-anabaseine dihydrochloride chemical structure
  5. BCC7651 Desformylflustrabromine hydrochloride Desformylflustrabromine hydrochloride is a selective agonist of α4β2 neuronal nicotinic acetylcholine receptor (nAChR) with a pEC50 of 6.48. Desformylflustrabromine hydrochloride chemical structure
  6. BCC7869 LY 2087101 913186-74-0 LY 2087101 chemical structure
  7. BCC7468 Sazetidine A dihydrochloride 1197329-42-2 Sazetidine A dihydrochloride chemical structure
  8. BCC7920 A 582941 848591-90-2 A 582941 chemical structure
  9. BCC6200 A 844606 861119-08-6 A 844606 chemical structure
  10. BCC7827 AR-R 17779 hydrochloride 178419-42-6 AR-R 17779 hydrochloride chemical structure
  11. BCC7948 GTS 21 dihydrochloride GTS-21 dihydrochloride is a selective α7 nicotinic acetylcholine receptor agonist, has recently been established as a promising treatment for inflammation. GTS 21 dihydrochloride chemical structure

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