Schizophrenia Research

Schizophrenia is a chronic, debilitating mental disorder affecting 1-2% of the global population. Symptoms are split into two types; 'positive' symptoms, including delusions and hallucinations, and 'negative' symptoms, including anhedonia and lack of motivation. Studies suggest that genetics, early environment, neurobiology, psychological and social processes are important contributory factors; some recreational and prescription drugs appear to cause or worsen symptoms. Several neurobiological alterations in brain structure, physiology and neurochemistry have been documented, along with an ever-increasing list of susceptibility genes.

Schizophrenia Research Products Targets

Products for Schizophrenia Research - Page 27

  1. Cat.No. Product Name Information/Activity
  2. BCC4357 Tizanidine HCl Tizanidine hydrochloride is an α2-adrenergic receptor agonist and inhibits neurotransmitter release from CNS noradrenergic neurons. Tizanidine HCl chemical structure
  3. BCC5226 UK 14,304 Brimonidine (UK 14304) is a full α2-adrenergic receptor (α2-AR) agonist. UK 14,304 chemical structure
  4. BCC7336 A 80426 mesylate 152148-64-6 A 80426 mesylate chemical structure
  5. BCC6851 ARC 239 dihydrochloride 55974-42-0 ARC 239 dihydrochloride chemical structure
  6. BCC7521 Atipamezole hydrochloride Atipamezole hydrochloride is a synthetic α2-adrenoceptor antagonist with a Ki of 1.6 nM. Atipamezole hydrochloride chemical structure
  7. BCC6948 BRL 44408 maleate 681806-46-2 BRL 44408 maleate chemical structure
  8. BCC6797 Efaroxan hydrochloride 89197-00-2 Efaroxan hydrochloride chemical structure
  9. BCC6798 Idazoxan hydrochloride Idazoxan hydrochloride (RX 781094 hydrochloride) is an α2-adrenoceptor antagonist and is also a imidazoline receptors (IRs) antagonist competitively antagonized the centrally induced hypotensive effect of imidazoline-like drugs (IMs). Idazoxan hydrochloride also improves motor symptoms in Parkinson’s disease, L-DOPA-induced dyskinesias, and experimental Parkinsonism. Idazoxan hydrochloride chemical structure
  10. BCC6875 Imiloxan hydrochloride 81167-22-8 Imiloxan hydrochloride chemical structure
  11. BCC7449 JP 1302 dihydrochloride JP1302 dihydrochloride is a selective, high affinity antagonist of the alpha2C-adrenoceptor (α2C-adrenoceptor), with a Kb value (antagonist activity) of 16 nM and a Ki (binding affinity) value of 28 nM. JP 1302 dihydrochloride chemical structure

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