Schizophrenia Research

Schizophrenia is a chronic, debilitating mental disorder affecting 1-2% of the global population. Symptoms are split into two types; 'positive' symptoms, including delusions and hallucinations, and 'negative' symptoms, including anhedonia and lack of motivation. Studies suggest that genetics, early environment, neurobiology, psychological and social processes are important contributory factors; some recreational and prescription drugs appear to cause or worsen symptoms. Several neurobiological alterations in brain structure, physiology and neurochemistry have been documented, along with an ever-increasing list of susceptibility genes.

Schizophrenia Research Products Targets

Products for Schizophrenia Research - Page 17

  1. Cat.No. Product Name Information/Activity
  2. BCC1114 Mianserin HCl Mianserin hydrochloride (Org GB 94) is a H1 receptor inverse agonist and is a psychoactive agent of the tetracyclic antidepressant. Mianserin HCl chemical structure
  3. BCC7218 AS 19 AS19 is a potent, selective 5-HT7 receptor agonist with an IC50 value of 0.83 nM and a Ki of 0.6 nM. AS19 is selective for 5-HT7 over 5-HT1A, 5-HT1B, 5-HT1D, and 5-HT5A receptors (Kis = 89.7 nM, 490 nM, 6.6 nM and 98.5 nM, respectively). AS19 enhances memory consolidation and reverses Scopolamine- or Dizocilpine-induced amnesia. AS 19 chemical structure
  4. BCC7517 LP 12 hydrochloride 1185136-22-4 LP 12 hydrochloride chemical structure
  5. BCC7399 LP 44 824958-12-5 LP 44 chemical structure
  6. BCC7990 DR 4485 hydrochloride 402942-53-4 DR 4485 hydrochloride chemical structure
  7. BCC7101 LY 215840 137328-52-0 LY 215840 chemical structure
  8. BCC5937 SB 258719 hydrochloride 1217674-10-6 SB 258719 hydrochloride chemical structure
  9. BCC5056 SB269970 HCl SB269970 hydrochloride (SB-269970A) is a hydrochloride salt form of SB-269970, which is a 5-HT7 receptor antagonist with the pKi of 8.3, exhibits >50-fold selectivity against other receptors. SB269970 HCl chemical structure
  10. BCC6681 8-Hydroxy-DPAT hydrobromide 76135-31-4 8-Hydroxy-DPAT hydrobromide chemical structure
  11. BCC6266 LP 20 hydrochloride 1386928-34-2 LP 20 hydrochloride chemical structure

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