Epilepsy Research

Epilepsy is a group of neurological conditions consisting of recurrent, usually unprovoked epileptic seizures. Epileptic seizures have recently been defined as "a transient occurrence of signs and/or symptoms due to abnormal, excessive or synchronous neuronal activity in the brain". Epilepsy is one of the most common disorders of the brain, with one in 10 people suffering at least one seizure in their lifetime. There are over 40 different types of epilepsy, each of which presents with its own unique combination of seizure type, typical age of onset, EEG findings, treatment, and prognosis.

Epilepsy Research Products Targets

Products for Epilepsy Research - Page 40

  1. Cat.No. Product Name Information/Activity
  2. BCC7936 VU 29 890764-36-0 VU 29 chemical structure
  3. BCC6969 (2R,4R)-APDC (2R,4R)-APDC is a selective group II metabotropic glutamate receptors (mGluRs) agonist. (2R,4R)-APDC has anticonvulsant and neuroprotective effects. (2R,4R)-APDC chemical structure
  4. BCC6609 L-CCG-l 117857-93-9 L-CCG-l chemical structure
  5. BCC5691 DCG IV DCG-IV is a potent agonist of group II mGluRs with EC50s of 0.35 and 0.09 μM for mGlu2R and mGlu3R, reapectively. DCG-IV is also a competitive antagonist at group I (IC50: mGlu1/5R=389/630 μM) and III receptors (IC50: mGlu4/6/7/8R= 22.5/39.6/40.1/32 μM). DCG-IV has anticonvulsive and neuroprotective effects. DCG IV chemical structure
  6. BCC7614 LY 354740 Eglumegad (LY354740) is a highly potent and selective group II (mGlu2/3) receptor agonist with IC50s of 5 and 24 nM on transfected human mGlu2 and mGlu3 receptors, respectively. LY 354740 chemical structure
  7. BCC7368 LY 379268 Highly selective group II mGlu agonist LY 379268 chemical structure
  8. BCC7623 (±)-LY 395756 852679-66-4 (±)-LY 395756 chemical structure
  9. BCC6758 MAP4 157381-42-5 MAP4 chemical structure
  10. BCC6925 (RS)-APICA 170847-18-4 (RS)-APICA chemical structure
  11. BCC6871 EGLU EGLU ((2S)-α-Ethylglutamic acid; (2S)-α-EGLU) is a potent and competitive mGluR-2 receptor antagonist. EGLU interacts with (lS,3S)-ACPD-sensitive site with a Kd value of 66 μM. EGLU is an antidepressant agent. EGLU chemical structure

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