Epilepsy Research

Epilepsy is a group of neurological conditions consisting of recurrent, usually unprovoked epileptic seizures. Epileptic seizures have recently been defined as "a transient occurrence of signs and/or symptoms due to abnormal, excessive or synchronous neuronal activity in the brain". Epilepsy is one of the most common disorders of the brain, with one in 10 people suffering at least one seizure in their lifetime. There are over 40 different types of epilepsy, each of which presents with its own unique combination of seizure type, typical age of onset, EEG findings, treatment, and prognosis.

Epilepsy Research Products Targets

Products for Epilepsy Research - Page 22

  1. Cat.No. Product Name Information/Activity
  2. BCC7339 ZK 200775 Fanapanel (ZK200775) is a highly selective AMPA/kainate antagonist with little activity against NMDA; have Ki values of 3.2 nM, 100 nM, and 8.5 μM against quisqualate, kainate, and NMDA, respectively. ZK 200775 chemical structure
  3. BCC6151 CMPDA CMPDA is a positive allosteric modulator of AMPA receptors with EC50s of 45.4 ± 4.2 nM/63.4 ± 5.6 nM for GluA2i/GluA2o receptor. CMPDA chemical structure
  4. BCC7532 CX 546 CX546 is a selective positive AMPAR modulator; the prototypical ampakine agent. CX 546 chemical structure
  5. BCC6759 Cyclothiazide 2259-96-3 Cyclothiazide chemical structure
  6. BCC5951 PEPA PEPA is an allosteric modulator of AMPA receptors; binds to the GluA2o and GluA3o LBDs and can be utilized as an indicator of AMPA receptor heterogeneity. PEPA chemical structure
  7. BCC6322 PF 4778574 PF-4778574 is a positive allosteric modulation of AMPA receptor with EC50 of 45 to 919 nM in differenct cells. PF 4778574 chemical structure
  8. BCC6081 S 18986 S 18986 is a selective, orally active, brain penetrant positive allosteric modulator of AMPA-type receptors. S 18986 shows cognitive enhancing properties in rodents. S 18986 activates the release of noradrenaline and acetylcholine in rat hippocampus and enhances rat memory in object-recognition tests. S 18986 chemical structure
  9. BCC4219 Aniracetam Aniracetam(Ro 13-5057) is a nootropics and neuroprotective drug, which is selectively modulates the AMPA receptor and nAChR. Aniracetam chemical structure
  10. BCC6974 IDRA 21 22503-72-6 IDRA 21 chemical structure
  11. BCC5787 pep2-AVKI 1315378-69-8 pep2-AVKI chemical structure

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