Immunology Research
Immunology is a branch of science that studies all aspects of the immune system, ranging from normal physiological functioning through to malfunctions which can lead to immunological diseases. Disorders that result from aberrant activation of the immune system are termed autoimmune diseases.
Immunology Research Products Areas
Products for Immunology Research - Page 54
- Cat.No. Product Name Information/Activity
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BCC7232
XE 991 dihydrochloride
XE 991 dihydrochloride, a Kv7 (KCNQ) channels blocker, potently inhibits Kv7.1 (KCNQ1), Kv7.2 (KCNQ2), Kv7.2 + Kv7.3 (KCNQ3) channel, and M-current with IC50s of 0.75 µM, 0.71 µM, 0.6 μM, and 0.98 µM, respectively.
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BCC7161
2-Chloro-N6-cyclopentyladenosine
Potent, selective A<sub>1</sub> agonist
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BCC7160
N6-Cyclopentyladenosine
N6-Cyclopentyladenosine (CPA) is a selective Adenosine A1 receptor agonist, with Ki values of 2.3 nM, 790 nM and 43 nM for human A1, A2A and A3 receptors, respectively.
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BCC7716
(±)-5'-Chloro-5'-deoxy-ENBA
Highly selective A<sub>1</sub> agonist
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BCC7215
GR 79236
GR79236 is a highly potent and selective adenosine A1 receptor agonist (Ki = 3.1 nM) that has analgesic and anti-inflammatory actions in humans and animals.
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BCC7311
2'-MeCCPA
205171-12-6
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BCC7374
SDZ WAG 994
130714-47-5
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BCC6664
1,3-Dipropyl-8-phenylxanthine
85872-53-3
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BCC6649
DPCPX
102146-07-6
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BCC6124
KW 3902
Rolofylline (KW-3902) is a potent, selective adenosine A1 receptor antagonist that is under development for the treatment of patients with acute congestive heart failure and renal impairment. Rolofylline is metabolized primarily to the pharmacologically active M1-trans and M1-cis metabolites by cytochrome P450 (CYP450). Rolofylline is alleviating the presynaptic dysfunction and restores neuronal activity as well as dendritic spine levels in vitro, is an interesting candidate to combat the hypometabolism and neuronal dysfunction associated with Tau-induced neurodegenerative diseases.
