Immunology Research
Immunology is a branch of science that studies all aspects of the immune system, ranging from normal physiological functioning through to malfunctions which can lead to immunological diseases. Disorders that result from aberrant activation of the immune system are termed autoimmune diseases.
Immunology Research Products Areas
Products for Immunology Research - Page 49
- Cat.No. Product Name Information/Activity
-
BCC1120
XAV-939
XAV-939 is a potent tankyrase inhibitor that targets Wnt/β-catenin signaling. XAV-939 stabilizes axin by inhibiting tankyrase 1 and tankyrase 2 (IC50s of 5 and 2 nM, respectively), thereby stimulating β-catenin degradation. XAV939 binds tightly to the catalytic (PARP) domains of TNKS1 and TNKS2 (Kds of 99 and 93 nM, respectively).
-
BCC4074
Icilin
Icilin(AG 3-5) is a synthetic super-agonist of TRPM8 ion channel.
-
BCC7543
WS 12
WS-12 is an agonist of TRPM8 with an EC50 of 39 nM.
-
BCC6419
RQ-00203078
RQ-00203078 is a highly selective, potent and orally available TRPM8 antagonist (IC50 values are 5.3 and 8.3 nM for rat and human channels respectively), exhibits >350-fold selectivity for TRPM8 over TRPV4, TRPV1 and TRPA1.
-
BCC7834
AMTB hydrochloride
926023-82-7
-
BCC6367
Ononetin
487-49-0
-
BCC7989
9-Phenanthrol
484-17-3
-
BCC6244
TC-I 2000
1159996-20-9
-
BCC5199
U-73122
U-73122 is a phospholipase C (PLC) and 5-LO (5-lipoxygenase) inhibitor with an IC50of 1-2.1 µM for PLC.
-
BCC4950
Calcitriol
Calcitriol is the most active metabolite of vitamin D and also a vitamin D receptor (VDR) agonist.
