Cardiovascular Research

The cardiovascular, or circulatory, system is a closed elastic circuit consisting of the heart, blood vessels (arteries, capillaries and veins) and the blood. The primary function is to pump oxygenated blood to the tissues throughout the body and reabsorb waste carbon dioxide for its removal. This function is performed by the use of pulmonary and systemic circulation.

Cardiovascular Research Products Areas

Products for Cardiovascular Research - Page 76

Cat.No. Product Name Information/Activity
BCC6828 Palmitoylethanolamide Impulsin (AM 3112) is an active endogenous compound which can used for preventing virus infection of the respiratory tract.
BCC2265 WY-14643 (Pirinixic Acid) Pirinixic acid (Wy-14643) is a potent agonist of PPARα, with EC50s of 0.63 μM, 32 μM for murine PPARα and PPARγ, and 5.0 μM, 60 μM, 35 μM for human PPARα, PPARγ and PPARδ, respectively.
BCC2267 GW0742 GW0742 is a potent PPARβ and PPARδ agonist, with an IC50 of 1 nM for human PPARδ in binding assay, and EC50s of 1 nM, 1.1 μM and 2 μM for human PPARδ, PPARα, and PPARγ, respectively.
BCC2268 GW501516 GW 501516 is a PPARδ agonist with an EC50 of 1.1 nM.
BCC1573 FH535 FH535 is an inhibitor of Wnt/β-catenin and PPAR, with anti-tumor activities.
BCC7688 GSK 0660 GSK0660 is a potent antagonist of PPARβ and PPARδ, with IC50s of 155 nM for both isoforms.
BCC2263 GSK3787 GSK3787 is as a selective and irreversible antagonist of PPARδ with pIC50 of 6.6, with no measurable affinity for hPPARα or hPPARγ.
BCC7014 Ciglitazone 74772-77-3
BCC7786 LG 100754 LG100754 (UVI 2112) is a RXR dimers modulater. LG100754 acts as a RXR:RXR homodimer antagonist, but functions as a agonist towards RXR:PPARα and RXR:PPARγ heterodimers. LG100754 is an insulin sensitizer that functions through RXR.
BCC7268 nTZDpa 118414-59-8