Cardiovascular Research
The cardiovascular, or circulatory, system is a closed elastic circuit consisting of the heart, blood vessels (arteries, capillaries and veins) and the blood. The primary function is to pump oxygenated blood to the tissues throughout the body and reabsorb waste carbon dioxide for its removal. This function is performed by the use of pulmonary and systemic circulation.
Cardiovascular Research Products Areas
Products for Cardiovascular Research - Page 22
- Cat.No. Product Name Information/Activity
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BCC7393
L-161,982
L-161982 is a selective EP4 receptor antagonist. L-161982 completely blocks PGE2-induced ERK phosphorylation and cell proliferation of HCA-7 cells. L-161982 alleviates collagen-induced arthritis in mice.
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BCC7156
L-655,240
103253-15-2
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BCC5857
L-670,596
121083-05-4
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BCC7654
L-798,106
L-798106 is potent and highly selective prostanoid EP3 receptor antagonist (Ki=0.3 nM), it also has micromolar activities at the EP4, EP1 and EP2 receptors with Ki values of 916 nM, >5000 nM and >5000 nM at EP4, EP1 and EP2, respectively.
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BCC1822
ONO-AE3-208
High affinity and selective EP<sub>4</sub> antagonist,ONO-AE3-208 is an <b>EP4</b> antagonist, and suppresses cell invasion, migration, and metastasis of prostate cancer.
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BCC6299
PF 04418948
PF-04418948 is an orally active, potent and selective prostaglandin EP2 receptor antagonist with an IC50 of 16 nM.
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BCC6968
SC 19220
19395-87-0
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BCC7773
SC 51089
146033-02-5
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BCC5941
SC 51322
146032-79-3
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BCC6184
Fatostatin A
298197-04-3
